ascochlorin suppliers
ascochlorin
- CAS:
- 26166-39-2
- MF:
- C23H29ClO4
- MW:
- 404.931
Suppliers by country/region
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Properties
- Melting point:
- 172-174 °C
- Boiling point:
- 556.9±39.0 °C(Predicted)
- Density
- 1.199±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- A powder
- pka
- 6.26±0.50(Predicted)
Safety Information
- WGK Germany
- 3
- Toxicity
- mouse,LD50,intraperitoneal,20mg/kg (20mg/kg),Journal of Antibiotics. Vol. 21, Pg. 539, 1968.
Use
Ascochlorin is an isoprenoid antibiotic and antiviral that has diverse effects on mammalian cells. It suppresses PMA-induced invasion in renal carcinoma cells (IC50 = ~10 μM) by inhibiting the expression of matrix metalloproteinase-9. At 2 μM, ascochlorin profoundly increases the expression of p53 by increasing protein stability in cancer cells, and, at 50 μm, it inhibits signaling through STAT3. Ascochlorin also binds and inhibits the mitochondrial cytochrome bc1 complex, blocking reduction of cytochrome b by ubiquinone.[Cayman Chemical]
25 supplier list of "ascochlorin"
-
0.5MG$549.001MG$1044.75
- Product Name:ASCOCHLORIN
- Products Intro:Brand:Acccorporation | OriginalID:API0025816 | Purity:95.00%
- Company Type: Trader
- Country/Region: UNITED STATES
You can find ascochlorin suppliers,
manufacturers, and distributors from countries such as United States, China here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.