CARBACYCLIN suppliers
CARBACYCLIN
- CAS:
- 69552-46-1
- MF:
- C21H34O4
- MW:
- 350.49
Suppliers by country/region
Properties
- Melting point:
- 65-67℃
- Boiling point:
- 514.8±50.0 °C(Predicted)
- Density
- 1.177±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble at 20mg/ml in ethanol.
- pka
- 4.77±0.10(Predicted)
- form
- Solid
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H312-H332
- Precautionary statements
- P261-P280h-P301+P312a-P304+P340-P321-P501a
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22
- Safety Statements
- 22-36
- WGK Germany
- 3
Use
Carbacyclin is a stable analog of PGI2. When infused in rabbits or dogs, it inhibits ex vivo platelet aggregation, but the effect persists only 10 minutes after termination of the infusion. Carbacyclin is a stable analog of PGI2. Carbacyclin inhibits platelet aggregation with 10% of the molar potency exhibited by PGI2. The ED50 of Carbacyclin for the in vitro inhibition of ADP-induced platelet aggregation in human PRP is 47 nM. It was also shown to effect terminal differentiation of preadipose into adipose cells and enhance the expression of angiotensinogen and adipose fatty acid binding protein with an EC50 of about 0.5 μM.
32 supplier list of "CARBACYCLIN"
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