Cyprodinil manufacturers and suppliers

Cyprodinil suppliers

Properties

Melting point:: 75.9°

Boiling point:: 406.0±48.0 °C(Predicted)

Density: 1.21 g/cm3

vapor pressure: 5.1 x l0^-4 Pa (25 °C)

storage temp.: 0-6°C

solubility: Chloroform: Slightly Soluble

pka: 4.44 (base)

Water Solubility: 20 mg l^-1 (pH 5), 13 mg l^-1 (pH 7), 15 mg l^-1 (pH 9) 25 °C

form: Solid

color: White to off-white

BRN: 7813601

LogP: 4.000

Safety Information

Symbol(GHS): GHS07,GHS09

Signal word: Warning

Hazard statements: H317-H410

Precautionary statements: P261-P272-P273-P280-P302+P352-P333+P313

Hazard Codes: Xi

Risk Statements: 36/38-43

Safety Statements: 26-36

RIDADR: UN 3077

WGK Germany: 2

Toxicity: LD50 orally or dermally in rats: >2000 mg/kg (Heye)

Use

After single oral administration of 14C-cyprodinil to rats, cyprodinil is rapidly eliminated principally in the urine. The pattern of the metabolic profile in the urine exhibits a significant sex-related difference with respect to the major metabolite. Males and females both produce N-4- (hydroxyphenyl)-4-cyclopropyl-5-hydroxy-6- methylpyrimidin-2-yl-amine. Female rats conjugate this dihydroxy metabolite with sulfate exclusively at the 5- hydroxypyrimidinyl moiety, while males form equal amounts of the monosulfate and disulfate conjugates. Ten cultures of 12 collected microorganisms produce a monohydroxylated metabolite and the filamentous fungus, Beauveria bassiana ATCC 7159, produces a methoxylated glycoside of the monohydroxylated metabolite. Dihydroxylated metabolites and a molecular cleavage product, 4-cyclopropyl-6-methyl-2- pyrimidinylamine, are detected in certain cultures.

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