Epothilone A suppliers
Epothilone A
- CAS:
- 152044-53-6
- MF:
- C26H39NO6S
- MW:
- 493.66
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Company Type
Properties
- Melting point:
- 95℃
- alpha
- D21 -47.1° (c = 1.0 in methanol)
- Boiling point:
- 683.3±55.0 °C(Predicted)
- Density
- 1.143
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- pka
- 13.57±0.70(Predicted)
- form
- solid
- color
- White to Off-White
- Stability:
- Stable under recommended storage conditions., Stable Under Recommended Storage C
Safety Information
- WGK Germany
- 3
Use
Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol binding site, and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A has been investigated in clinical trials as an antitumour agent.The epothilones are a novel class of antineoplastic agents possessing antitubulin activity. Epothilone A, B isolated from Sorangium cellulosum was associated with cell cycle arrest at G2/M transition and apoptosis that was resisted with overexpression of β-tubulin and P-glycoprotein in human bladder carcinoma cell.
93 supplier list of "Epothilone A"
$1.00/ 1KG
- Product Name:Epothilone A
- Products Intro:Purity: 99% | Package: 1KG;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information