EPZ015666 suppliers
EPZ015666
- CAS:
- 1616391-65-1
- MF:
- C20H25N5O3
- MW:
- 383.44
Suppliers by country/region
Company Type
Properties
- Melting point:
- 124-131°C
- Boiling point:
- 686.4±55.0 °C(Predicted)
- Density
- 1.331±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO (up to 20 mg/ml)
- pka
- 12.40±0.46(Predicted)
- form
- powder
- color
- white to beige
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
- CAS DataBase Reference
- 1616391-65-1
Safety Information
Use
EPZ015666 (GSK3235025) is an orally available inhibitor of protein arginine methyltransferase-5 (PRMT5), which is involved in diverse cellular processes, including tumorigenesis, and its overexpression is observed in cell lines and primary patient samples derived from lymphomas, particularly mantle cell lymphoma (MCL).EPZ015666 showed dose-dependent antitumor activity in multiplein vitroandin vivomantle cell lymphoma (MCL) models with treatment of MCL cell lines leading to inhibition of SmD3 methylation and cell death. Therefore, it is a potential drug candidate for future cancer therapy.
82 supplier list of "EPZ015666"
- Product Name:EPZ015666
- Products Intro:Purity: 99.92% | Package: 2mg;56USD|5mg;85USD|10mg;126USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:EPZ015666;GSK3235025
- Products Intro:Package: 1 mg;1 mL * 10mM (in DMSO);10 mg;100 mg;2 mg;5 mg;50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:EPZ015666
- Products Intro:Purity: 98% (HPLC) | Package: $107.9/5mg;$486.9/25mg;$489.9/50mg;$706.9/100mg;Bulk package | CustNote: 98% (HPLC)
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
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