EUK 118 manufacturers and suppliers

EUK 118 suppliers

EUK 118

CAS:: 186299-34-3

MF:: C22H25MnN2O8

MW:: 500.39

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Properties

solubility: DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.2 mg/ml

form: A crystalline solid

Safety Information

Use

EUK 8 and EUK 134 are synthetic catalytic scavengers of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity. EUK 118 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity. EUK 118 exhibits a catalase activity of 35 μM O2 formed/minute from 10 mM hydrogen peroxide, which is more than four times lower that that observed for EUK 8 under the same conditions. Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 and EUK 8 with IC50 values of 2 and 0.7 μM, respectively. EUK 118 did not protect human dermal fibroblasts against hydrogen peroxide-induced cell death.

You can find EUK 118 suppliers, manufacturers, and distributors from countries such as China, United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.