Fasudil hydrochloride suppliers
Fasudil hydrochloride
- CAS:
- 105628-07-7
- MF:
- C14H18ClN3O2S
- MW:
- 327.83
Suppliers by country/region
Company Type
Properties
- Melting point:
- 220.5°; mp 219.3° (Shirotani)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- H2O: >200 mg/mL
- form
- solid
- color
- white
- Water Solubility
- Soluble in water and dimethyl sulfoxide. Insoluble in ethanol.
- Merck
- 14,3942
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
- InChI
- InChI=1S/C14H17N3O2S.2ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;;/h1,3-5,7,11,15H,2,6,8-10H2;2*1H
- InChIKey
- LFVPBERIVUNMGV-UHFFFAOYSA-N
- SMILES
- N1(S(C2=CC=CC3=C2C=CN=C3)(=O)=O)CCCNCC1.[H]Cl.[H]Cl
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312+P330-P501-P301+P312a-P330-P501a
- Risk Statements
- 22
- Safety Statements
- 36-60
- WGK Germany
- 3
- RTECS
- HM4031166
- HS Code
- 29339900
- Toxicity
- LD50 in mice, rats (mg/kg): 67.5, 59.9 i.v.; 124.5, 123.2 s.c.; 273.9, 335.0 orally (Koga)
Use
Fasudil Hydrochloride is an isoquinoline sulfonamide derivative which can relax separated cerebral blood vessels, inhibit the shrinkage of separated blood vessels caused by calcium influx, inhibit different mechanisms of brain blood vessel contraction from contractile agents, and inhibit intracellular calcium ion activity without reducing calcium ion concentration. Fasudil Hydrochloride is an RHO kinase inhibitor which dilates vessels, reduces tension of endothelial cells, and improves microcirculation of brain tissue without producing or exacerbating diversion of blood to the brain, by increasing activity of myosin light chain phosphatase. At the same time, it can protect nerves against apoptosis and promote their regeneration. Fasudil Hydrochloride promotes recovery of neural function and reduces clinical symptoms.
349 supplier list of "Fasudil hydrochloride"
![Fasudil Hydrochloride](/images/pro-3.jpg)
- Product Name:Fasudil Hydrochloride
- Company Type: Manufacturer
- Country/Region: CHINA
$0.00/ 25KG
- Product Name:Fasudil hydrochloride
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$30.00-10.00 / 1kg
- Product Name:Fasudil hydrochloride
- Products Intro:Purity: 0.99|Package: 1kg;30.00;USD|25kg;25.00;USD|100kg;10.00;USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate
$10.00-3.00 / 1kg
- Product Name:Fasudil Hydrochloride
- Products Intro:Purity: 99% | Package: 1kg;10USD|25kg;5USD|180kg;3USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
$0.00/ 1kg
- Product Name: Fasudil Hydrochloride
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA