GNE-3511 suppliers
GNE-3511
- CAS:
- 1496581-76-0
- MF:
- C23H26F2N6O
- MW:
- 440.49
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 579.0±50.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO:25.63(Max Conc. mg/mL);58.18(Max Conc. mM)
Methanol:1.0(Max Conc. mg/mL);2.27(Max Conc. mM)
- form
- A crystalline solid
- pka
- 7.23±0.40(Predicted)
- color
- Light yellow to yellow
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
- HS Code
- 2934999090
Use
GNE-3511 is a selective and highly potent inhibitor of dual leucine zipper kinase (DLK). It also inhibits phosphorylated JNKand is highly selective for DLK over other MAP kinases. In an MPTP mouse model of Parkinsons disease, a high dose of GNE-3511 completely suppresses phosphorylated c-Jun (p-c-Jun) expression, while a low dose moderately reduces its expression. Study has also shown that GNE03511 displayed concentration-dependent protection of neurons from degeneration in vitro and demonstrated dose-dependent activity in two different animal models of disease. These results suggest that GNE-3511 may have therapeutic potential in multiple indications.
50 supplier list of "GNE-3511"
- Product Name:GNE-3511
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:GNE-3511
- Products Intro:Purity: 98% | Package: 50mg | CustNote: BOC Sciences also provides custom synthesis services for GNE-3511.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:GNE-3511
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: GNE-3511
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:GNE-3511
- Products Intro:Purity: NLT 98% | Package: 1G;100G;1KG;50KG | CustNote: MC714376
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
- Product Name:GNE-3511
- Products Intro:Purity: 98 | Package: 500mg；1g；5g；10g；25g | CustNote: Provide customized services
- Company Type: Trader
- Country/Region: CHINA
- Product Name:GNE-3511
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:GNE-3511
- Products Intro:Purity: 99% | Package: $90.9/10mg;$150.9/25mg;$250.9/50mg;$400.9/100mg;Bulk package | CustNote: 99%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:GNE-3511
- Products Intro:Purity: 0.98 | Package: 10G:100G
- Company Type: Trader
- Country/Region: CHINA
- Main Products: MRTX1133,(cas:2055858-27-8)1,1′-Sulfinylbis[3,5-difluorobenzene,(cas:17220-38-1) 3,4-Diaminofurazane,Mirogabalin besylate,AK2292
- Product Name:GNE-3511
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A905133
- Company Type: Reagent
- Country/Region: CHINA
-
1 mg$34.005 mg$119.0010 mg$170.0025 mg$383.00
- Product Name:GNE-3511
- Products Intro:Brand: Caymanchem | Product Number: 19174 | Purity: ≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof
You can find GNE-3511 suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.