GRAMICIDIN A suppliers
GRAMICIDIN A
- CAS:
- 11029-61-1
- MF:
- C99H140N20O17
- MW:
- 1882.29
Suppliers by country/region
Company Type
Properties
- storage temp.
- 2-8°C
- solubility
- ethanol: soluble
- form
- White to off-white solid
- color
- colorless or white
- BRN
- 6461131
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
- Hazard Codes
- Xn
- Risk Statements
- 22
- WGK Germany
- 3
- RTECS
- MD8230000
- Toxicity
- mouse,LD50,intraperitoneal,60mg/kg (60mg/kg),"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 240, 1980.
Use
Purify gramicidin A by countercurrent distribution from *C6H6/CHCl3, MeOH/H2O (15:15:23:7) with 5000 tubes. Fractions are examined by UV (280nm) of small aliquots. Separation from gramicidin C and other material occurred after 999 transfers. [Gross & Witkop Biochemistry 4 2495 1965, Bauer et al. Biochemistry 11 3266 1972.] Purify it finally by recrystallisation from EtOH/H2O and dry it at 100o/10-2mm over KOH. It forms platelets m 229-230o. It is almost insoluble in H2O (0.6%) but soluble in lower alcohols, dry Me2CO, dioxane, acetic acid and pyridine. The commercial material is more difficult to crystallise than the synthetic compound. [Sarges & Witkop J Am Chem Soc 86 1861 1964, 87 2011, 2020 1965.] It has characteristic [] D20 +27.3o (c 1.3, MeOH) and UV max at 282nm ( 22,100). The N-carbamoyldeformyl gramicidine A precipitates from EtOAc/pet ether (b 40-60o). [Beilstein 26 III/IV 4273.]
73 supplier list of "GRAMICIDIN A"
$1.10/ 1g
- Product Name:GRAMICIDIN A
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
-
25mg$315.00
- Product Name:Gramicidin A, High Purity, Bacillus brevis - CAS 11029-61-1 - Calbiochem
- Products Intro:Brand: Sigma-Aldrich | Product Number: 368020 | Purity: Gramicidin A, High Purity, Bacillus brevis, CAS 11029-61-1, is a naturally-occurring ion channel-forming pentadecapeptide. Causes K+/H+ exchange in mitochondria in a non-voltage dependent manner.
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof