N-OXALYL GLYCINE suppliers
N-OXALYL GLYCINE
- CAS:
- 5262-39-5
- MF:
- C4H5NO5
- MW:
- 147.09
Suppliers by country/region
Company Type
Properties
- Density
- 1.638±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- deionized water: >10mg/mL
- form
- solid
- pka
- 2.83±0.20(Predicted)
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS07
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Signal word
- Warning
- Hazard statements
- H302
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P501
- Precautionary statements
- P264-P270-P301+P312-P501
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22
- WGK Germany
- 3
- HazardClass
- IRRITANT
Use
The jumonji domain-containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are candidate anticancer agents as well as potential tools for elucidating the biological functions of JMJDs. N-Oxalylglycine, the amide analog of α-ketoglutarate, is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes, including JMJD2A, JMJD2C, and JMJD2E (IC50s = 250, 500, and 24 μM, respectively). It can also inhibit the prolyl hydroxylase domain-containing proteins PHD1 and PHD2 with IC50 values of 2.1 and 5.6 μM, respectively.[Cayman Chemical]
87 supplier list of "N-OXALYL GLYCINE"
- Product Name:N-Oxalylglycine;Oxalylglycine
- Products Intro:Package: 10 mg;100 mg;200 mg;25 mg;5 mg;50 mg;500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:N-Oxalylglycine
- Products Intro:Purity: >=98% | Package: $139.9/100mg;$314.9/250mg;$1131.9/1g;$5090.9/5g;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies