PLERIXAFOR suppliers
PLERIXAFOR
- CAS:
- 110078-46-1
- MF:
- C28H54N8
- MW:
- 502.78
Suppliers by country/region
Company Type
Properties
- Melting point:
- 122-125°C
- Boiling point:
- 657.5±55.0 °C(Predicted)
- Density
- 0.962
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- pka
- 10.60±0.20(Predicted)
- color
- White to Pale Beige
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 110078-46-1
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H319-H315
- Precautionary statements
- P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
- HS Code
- 29339900
Use
Plerixafor inhibits CXCL12-mediated chemotaxis with a potency lightly better than its affinity for CXCR4. Plerixafor also antagonizes SDF-1/CXCL12 ligand binding with an IC50 of 651 nM. Plerixafor inhibits SDF-1 mediated GTP-binding, SDF-1 mediated calcium flux and SDF-1 stimulated chemotaxis with IC50 of 27 nM, 572 nM and 51 nM, respectively. Plerixafor does not inhibit calcium flux against cells expressing CXCR3, CCR1, CCR2b, CCR4, CCR5 or CCR7 when stimulated with their cognate ligands, nor does Plerixafor inhibit receptor binding of LTB4. Plerixafor does not, on its own, induce a calcium flux in the CCRF–CEM cells, which express multiple GPCRs including CXCR4, CCR4 and CCR7.
206 supplier list of "PLERIXAFOR"
$50.00/ 1kg
- Product Name:Plerixafor
- Products Intro:Purity: 99.9% | Package: 1kg;50USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediates,Peptides,Organic Chemical,Sarm Product,Pharmaceutical Chemical
$1.00/ 1kg
- Product Name:PLERIXAFOR
- Products Intro:Purity: 98% | Package: 1kg;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
![Plerixafor](/images/pro-3.jpg)
- Product Name:Plerixafor
- Products Intro:Purity: 0.99
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Plerixafor;AMD 3100;AMD-3329;JM3100
- Products Intro:Purity: >=95% | Package: 5mg;42USD|10mg;63USD|25mg;113USD | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits