Prilocaine manufacturers and suppliers

Prilocaine suppliers

Properties

Melting point:: 37-38°

Boiling point:: bp0.1 159-162°

Density: 1.0117 (rough estimate)

refractive index: nD20 1.5298

storage temp.: 2-8°C

solubility: Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent).

pka: pKa 7.32 or 7.89 (Uncertain)

form: Solid

color: White to off-white

Water Solubility: 6.169g/L(25 ºC)

InChI: InChI=1S/C13H20N2O/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2/h5-8,11,14H,4,9H2,1-3H3,(H,15,16)

InChIKey: MVFGUOIZUNYYSO-UHFFFAOYSA-N

SMILES: C(NC1=CC=CC=C1C)(=O)C(NCCC)C

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H319

Precautionary statements: P301+P312+P330-P305+P351+P338

HS Code: 2924296000

Use

Prilocaine metabolism has beenstudied extensively in animal models, less is known aboutthe human metabolites or the human CYP enzymes involvedin their formation . The metabolism of prilocainein the liver yields o-toluidine, which is a possiblecarcinogen. Many aromatic amines, including o-toluidinehave been shown to be mutagenic, and metabolites of otoluidinehave been shown to form DNA adducts.Metabolites of o-toluidine are also believed to be responsiblefor the methemoglobinemia observed with prilocaineuse. To decrease the potential for methemoglobinemia, strictadherence to the maximum recommended dose should befollowed. Metabolism of prilocaine is extensive with lessthan 5% of a dose excreted unchanged in the urine.

You can find Prilocaine suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.