Quetiapine fumarate manufacturers and suppliers

Quetiapine fumarate suppliers

Properties

Melting point:: 174-176°C

Flash point:: 9℃

storage temp.: 2-8°C

solubility: DMSO: >10mg/mL

form: powder

color: white to off-white

Merck: 14,8039

BCS Class: 2

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

InChIKey: VRHJBWUIWQOFLF-WLHGVMLRSA-N

SMILES: C(/C(=O)O)=C\C(=O)O.C(N1CCN(C2=NC3C=CC=CC=3SC3=CC=CC=C23)CC1)COCCO

CAS DataBase Reference: 111974-72-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS07,GHS09

Signal word: Warning

Hazard statements: H302-H400

Precautionary statements: P273-P301+P312+P330

Hazard Codes: Xn,N,T,F

Risk Statements: 22-50/53-52/53-39/23/24/25-23/24/25-11

Safety Statements: 60-61-45-36/37-16

RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany: 3

RTECS: KK3605000

HS Code: 29349990

Use

Quetiapine fumarate is an antipsychotic, successfully developed by the AstraZeneca United States, it interacts with a variety of neurotransmitter receptors, in the brain, it displays high degree affinity for serotonin (5-HT2) receptor, and it is greater than dopamine D1 and D2 dopamine receptor affinity in the brain. Quetiapine also has high affinity for histamine H1 receptor and adrenergic α1 receptors, and low affinity for α2 receptors, but it basically displays no affinity for cholinergic muscarinic receptors or benzodiazepine receptors . It shows positive results in antipsychotic activity assays such as conditioned avoidance reflex . In clinical, it is mainly used in treatment for adults with severe depression, acute manic episodes of bipolar disorder and schizophrenia of different types . It is not only effective for the positive symptoms of schizophrenia, but also having a certain effect for negative symptoms . It can also alleviate affective symptoms associated with schizophrenia, such as depression, anxiety symptoms and cognitive deficits. The above information is edited by the chemicalbook of Tian Ye.

You can find Quetiapine fumarate suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.