Rubitecan suppliers
Rubitecan
- CAS:
- 91421-42-0
- MF:
- C20H15N3O6
- MW:
- 393.35
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Properties
- Melting point:
- 182-186°C
- alpha
- D23 +27° (c = 0.2 in CH3OH-CHCl3, 1:4)
- Boiling point:
- 816.3±65.0 °C(Predicted)
- Density
- 1.63
- Flash point:
- 106℃
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Chloroform, Methanol
- form
- Solid
- pka
- 11.16±0.20(Predicted)
- color
- Yellow
- Merck
- 14,8288
Safety Information
Use
Rubitecan, marketed by Supergen as Orathecin, is a promising oral treatment for solid melanoma, prostate, breast, ovarian, and other cancers, as well as leukemia. It is a derivative of camptothecin, a topoisomerase inhibitor known from Chinese Traditional Medicine. It selectively targets the critical S-stage of cellular reproduction particularly in acidic environments, as in many cancer cells relaxing DNA supercoiling and generating lethal breaks in the DNA. Due to insolubility, its biological delivery mechanism is not yet effective, and it has not been approved for clinical use.
135 supplier list of "Rubitecan"
- Product Name:9-Nitrocamptothecin
- Products Intro:Purity: 0.98 | Package: 1KG;10KG;50KG
- Company Type: Trader
- Country/Region: CHINA
You can find Rubitecan suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here.
Browse to the tetrahydrofuran product information displayed by the supplier,
as well as the supplier's contact and capability information.