Siccanin suppliers
Siccanin
- CAS:
- 22733-60-4
- MF:
- C22H30O3
- MW:
- 342.47
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Properties
- Melting point:
- 139-140°
- alpha
- D20 -136° (c = 2 in chloroform)
- Boiling point:
- 427.8±45.0 °C(Predicted)
- Density
- 1.18±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- form
- A solid
- pka
- 10.9(at 25℃)
Safety Information
- Toxicity
- LD50 in mice, rats (mg/kg): >6000, >1000 orally; >3000, >600 s.c. or i.p. (Suzuki)
Use
Siccanin is an unusual, fused, phenolic pentacycle first isolated from Helminthosporium siccans and reported in 1962 as a potent antifungal agent. Siccanin inhibits succinate dehydrogenase in the terminal electron transport system. More recent studies note the proximity of the siccanin binding site to the quinone-binding site of the enzyme. Species-selective inhibition by siccanin is unique among succinate dehydrogenase inhibitors and offers a lead for new chemotherapeutics.
18 supplier list of "Siccanin"
You can find Siccanin suppliers,
manufacturers, and distributors from countries such as CHINA, United States and the South Korea here.
Browse to the tetrahydrofuran product information displayed by the supplier,
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