Stavudine suppliers
Stavudine
- CAS:
- 3056-17-5
- MF:
- C10H12N2O4
- MW:
- 224.21
Suppliers by country/region
Company Type
Properties
- Melting point:
- 159-160°C
- alpha
- D25 -39.4° (c = 0.701 in water); D20 -46.1° (c = 0.7 in water)
- Density
- 1.374±0.06 g/cm3(Predicted)
- refractive index
- -46 ° (C=0.69, H2O)
- storage temp.
- -20°C
- solubility
- Soluble in water, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride. It shows polymorphism (5.9).
- form
- Solid
- pka
- 9.47±0.10(Predicted)
- color
- White
- Water Solubility
- 5-10 g/100 mL at 21 ºC
- BCS Class
- 1,3
- Stability:
- Stable. Combustible. Incompatible with strong oxidizing agents.
- InChIKey
- XNKLLVCARDGLGL-JGVFFNPUSA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H341
- Precautionary statements
- P201-P202-P280-P308+P313-P405-P501
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 2
- RTECS
- XP2075000
- HS Code
- 29349990
- Toxicity
- LD50 oral in rat: 4gm/kg
Use
Stavudine, 2'3'-didehydro-2'-deoxythymidine (D4T, Zerit), isan unsaturated pyrimidine nucleoside that is related to thymidine.The drug inhibits the replication of HIV by a mechanismsimilar to that of its close congener, AZT.Stavudine is bioactivatedby cellular enzymes to a triphosphate.Stavudine is available as capsules for oral administration.The drug is acid stable and well absorbed (about 90%) followingoral administration. Stavudine has a short half-life(1–2 hours) in plasma and is excreted largely unchanged(85%–90%) in the urine.As with ddC, the primary doselimitingeffect is peripheral neuropathy. Stavudine isrecommended for the treatment of adults with advancedHIV infection who are intolerant of other approved therapiesor who have experienced clinical or immunological deteriorationwhile receiving these therapies.
380 supplier list of "Stavudine"
- Product Name:Stavudine;Sanilvudine;BMY-27857;NSC 163661;d4T
- Products Intro:Purity: 98.91% | Package: 1 mL * 10mM (in DMSO);100 mg;200 mg;500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits