Telithromycin suppliers
Telithromycin
- CAS:
- 191114-48-4
- MF:
- C43H65N5O10
- MW:
- 812
Suppliers by country/region
Company Type
Properties
- Melting point:
- 176-188 C
- Boiling point:
- 966℃
- Density
- 1.26±0.1 g/cm3(Predicted)
- RTECS
- KF4674500
- Flash point:
- >110°(230°F)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 10.85±0.70(Predicted)
- color
- White to Light Beige
- Water Solubility
- Sparingly soluble in water
- CAS DataBase Reference
- 191114-48-4(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H315-H319-H335-H400-H410
- Precautionary statements
- P261-P280a-P304+P340-P305+P351+P338-P405-P501a
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- HazardClass
- 9
- Hazardous Substances Data
- 191114-48-4(Hazardous Substances Data)
Use
Telithromycin (Ketek) is an orally bioavailable macrolide.The antibiotic is semisynthetic. Telithromycin is classifiedas a ketolide, and it differs chemically from the macrolidegroup of antibacterials by the lack of α-L-cladinose at 3-position of the erythronolide A ring, resulting in a 3-ketofunction. It is further characterized by imidazolyl andpyridyl rings inked to the macrolide nucleus through a butylchain. The mechanism of action of telithromycin is the sameas that of the macrolide class.Telithromycin causes a blockade of protein synthesis bybinding to domains II and V of 23S rRNA of the 50S ribosomalsubunit. Because telithromycin binds at domain II,activity against Gram-positive cocci is retained in the presenceof resistance mediated by methylases that alter thedomain V binding site. The antibiotic is also believed to inhibitthe assembly of ribosomes. Resistance to telithromycinoccurs because of riboprotein mutations.
157 supplier list of "Telithromycin"
$10.50/ 1KG
- Product Name:Telithromycin
- Products Intro:Purity: 99|Package: 1KG;10.50;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: acetic acid,Ethyl oleate,Hypophosphorous acid,tetramisole,OPP
- Product Name:Imidodisulfurylchloride
- Products Intro:Purity: 85.0-99.8% | Package: 1KG;USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$0.00/ 1G
- Product Name:Telithromycin
- Products Intro:Purity: 98%min | Package: 1G
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Linoleic Acid,Vitamin B12,Riboflavin,β-Nicotinamide Mononucleotide,Amoxicillin trihydrate