Teniposide suppliers
Teniposide
- CAS:
- 29767-20-2
- MF:
- C32H32O13S
- MW:
- 656.65
Suppliers by country/region
Company Type
Properties
- Melting point:
- 244-247°C
- alpha
- D20 -107° (9:1 chloroform/methanol)
- Boiling point:
- 650.86°C (rough estimate)
- Density
- 1.2568 (rough estimate)
- refractive index
- 1.5530 (estimate)
- storage temp.
- -20°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- pka
- 10.13(at 25℃)
- color
- white to beige
- optical activity
- [α]/D -100 to -115°, c = 1 in chloroform/methanol (9:1)
- λmax
- 283nm(MeOH)(lit.)
- Merck
- 14,9145
- Stability:
- Hygroscopic
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H341-H412
- Precautionary statements
- P202-P273-P280-P308+P313-P405-P501
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-45
- Safety Statements
- 26-36-45-53
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
- RTECS
- KC0180000
- HS Code
- 29349990
- Toxicity
- LD50 intraperitoneal in mouse: 29570ug/kg
Use
Teniposide is available in 50-mg ampules with Cremophor ELfor IV administration in the treatment of acute lymphoblasticleukemia (ALL). The agent is more potent as an inhibitor oftopoisomerase II. The pharmacokinetics of teniposide issimilar to that of etoposide; however, the more lipophilic teniposideis more highly protein bound (99%) and less isexcreted unchanged in the urine (10%–20%). There is alsogreater overall metabolism of teniposide; however, CYP3A4-mediated conversion to the active catechol is slower comparedwith etoposide. Elimination occurs primarily in the urine witha terminal elimination half-life of 5 hours.
167 supplier list of "Teniposide"
$1.00/ 1kg
- Product Name:Teniposide
- Products Intro:Purity: 95%-99% | Package: 1kg;1USD
- Company Type: Reagent
- Country/Region: CHINA
$1.10/ 1g
- Product Name:Teniposide
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Teniposide
- Products Intro:Purity: 98%min | Package: 1Kg/Bag;USD
- Company Type: Trader
- Country/Region: CHINA