TROLEANDOMYCIN manufacturers and suppliers

TROLEANDOMYCIN suppliers

Properties

Melting point:: 170 °C

alpha: D25 -23° (methanol)

Boiling point:: 757°C (rough estimate)

Density: 1.1651 (rough estimate)

refractive index: 1.6220 (estimate)

storage temp.: 0-6°C

solubility: Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 25 mg/ml).

form: White solid.

pka: 6.6(at 25℃)

color: White

Water Solubility: 0.25g/L(28 ºC)

Merck: 13,9839

Stability:: Stable for 2 years as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H332-H315-H319

Precautionary statements: P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P261-P271-P304+P340-P312

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 22-24/25-36-26

WGK Germany: 2

RTECS: RJ9900000

F: 8

Toxicity: LD50 oral in mouse: > 5gm/kg

Use

Oleandomycin contains three hydroxyl groups that aresubject to acylation, one in each of the sugars and one in theoleandolide. The triacetyl derivative retains the in vivo antibacterialactivity of the parent antibiotic but possesses superiorpharmacokinetic properties. It is hydrolyzed in vivo tooleandomycin.

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