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ChemicalBook >> CAS DataBase List >>XL518

XL518 suppliers

XL518

CAS:
934660-93-2
MF:
C21H21F3IN3O2
MW:
531.31

Properties

Melting point:
165 - 166°C
Boiling point:
565.9±50.0 °C(Predicted)
Density 
1.706
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
13.13±0.20(Predicted)
color 
Off-White

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
HS Code 
29333990

Use

A potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. It inhibits proliferation and stimulates apoptosis in a variety of human tumor cell lines. In preclinical xenograft models, oral administration of XL518 results in sustained inhibition of pERK in tumor tissue, but not brain tissue, leading to tumor growth inhibition and regression at well tolerated doses.

130 supplier list of "XL518"

  • Product Name:Cobimetinib
  • Products Intro:Purity: As coa | Package: As request | CustNote: 934660-93-2
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Cobimetinib
  • Products Intro:Purity: 98+% | Package: 25g;50g;100g;500g;1kg;10kg;50kg
  • Company Type: Reagent
  • Country/Region: CHINA

$2.00/ 1kg

  • Product Name:XL518
  • Products Intro:Purity: 99% | Package: 1kg;2USD
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:Cobimetinib
  • Products Intro:Purity: >=98% | Package: 25mg | CustNote: BOC Sciences also provides custom synthesis services for Cobimetinib.
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:XL518
  • Products Intro:Purity: 0.98 | Package: 1kg,2kg,5kg,10kg,25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
  • Product Name:Cobimetinib
  • Products Intro:Purity: 99%min | Package: 10G;USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:XL518
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:COBIMETINIB(XL518)
  • Products Intro:Purity: 99% | Package: USP EP CP
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Pharmceutical,Optical Brightening,dyes
  • Product Name:Cobimetinib
  • Products Intro:Purity: 0.99 | Package: 5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials
  • Product Name:Cobimetinib
  • Products Intro:Purity: 0.95&0.99 | Package: 0.1KG;1KG;1000KG | CustNote: Factory Supply
  • Company Type: Trader
  • Country/Region: CHINA
You can find XL518 suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

XL518 Related Search:

DONEPEZIL HYDROCHLORIDEPonatinibCrizotinibTofacitinibRuxolitinibVandetanib Osimertinib mesylateCeritinib (LDK378)NintedanibAlectinibAfatinibPalbociclibIbrutinibLenvatinibPanitumumabCapecitabineRibonucleic acid(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one
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