N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea
- $47 - $7364
- Product name: N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea
- CAS: 1020172-07-9
- MF: C30H28FN7O3
- MW: 553.59
- EINECS:
- MDL Number:MFCD19443646
- Synonyms:Rebastinib;DCC-2036 (Rebastinib);N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(MethylcarbaMoyl)pyridin-4-yl);1-(3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl)-3-(2-fluoro-4-(2-(methylcarbamoyl)pyridin-4-yloxy)phenyl)urea;N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea DCC-2036 (Rebastinib);Rebastinib(DCC-2036);N-[3-tert-Butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]-N'-[2-fluoro-4-[(2-(methylcarbamoyl)pyridin-4-yl)oxy]phenyl]urea;Rebastinib Tosylate
28 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- TRC
Package
- 1mg
- 5mg
- 10mg
- 2x5mg
- 25mg
- 50mg
- 100mg
- 200MG
- 250mg
- 500mg
- 5g
- 10mM(in 1mL DMSO)
- 1g
- ManufacturerAK Scientific
- Product numberX7511
- Product descriptionRebastinib
- Packaging1g
- Price$2523
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001381
- Product descriptionREBASTINIB 95.00%
- Packaging200MG
- Price$2800
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1404
- Product descriptionDCC-2036(Rebastinib)
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1404
- Product descriptionDCC-2036(Rebastinib)
- Packaging10mM(in 1mL DMSO)
- Price$121
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1404
- Product descriptionDCC-2036(Rebastinib)
- Packaging10mg
- Price$157
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1404
- Product descriptionDCC-2036(Rebastinib)
- Packaging50mg
- Price$627
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2123
- Product descriptionDCC2036-Rebastinib 99%
- Packaging2x5mg
- Price$198
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146234
- Product descriptionDCC-2036 (Rebastinib) >98%
- Packaging100mg
- Price$765
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146234
- Product descriptionDCC-2036 (Rebastinib) >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb146234
- Product descriptionDCC-2036 (Rebastinib) >98%
- Packaging1g
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64998
- Product descriptionDCC 2036
- Packaging10mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64998
- Product descriptionDCC 2036
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64998
- Product descriptionDCC 2036
- Packaging100mg
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64998
- Product descriptionDCC 2036
- Packaging250mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD64998
- Product descriptionDCC 2036
- Packaging500mg
- Price$1000
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21465
- Product descriptionRebastinib ≥98%
- Packaging1mg
- Price$47
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | X7511 | Rebastinib | 1g | $2523 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001381 | REBASTINIB 95.00% | 200MG | $2800 | 2021-12-16 | Buy |
ApexBio Technology | B1404 | DCC-2036(Rebastinib) | 5mg | $104 | 2021-12-16 | Buy |
ApexBio Technology | B1404 | DCC-2036(Rebastinib) | 10mM(in 1mL DMSO) | $121 | 2021-12-16 | Buy |
ApexBio Technology | B1404 | DCC-2036(Rebastinib) | 10mg | $157 | 2021-12-16 | Buy |
ApexBio Technology | B1404 | DCC-2036(Rebastinib) | 50mg | $627 | 2021-12-16 | Buy |
Axon Medchem | Axon2123 | DCC2036-Rebastinib 99% | 2x5mg | $198 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146234 | DCC-2036 (Rebastinib) >98% | 100mg | $765 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146234 | DCC-2036 (Rebastinib) >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb146234 | DCC-2036 (Rebastinib) >98% | 1g | $2691.1 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD64998 | DCC 2036 | 10mg | $65 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD64998 | DCC 2036 | 50mg | $250 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD64998 | DCC 2036 | 100mg | $400 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD64998 | DCC 2036 | 250mg | $750 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD64998 | DCC 2036 | 500mg | $1000 | 2021-12-16 | Buy |
Cayman Chemical | 21465 | Rebastinib ≥98% | 1mg | $47 | 2024-03-01 | Buy |
Properties
Melting point :>181°C (dec.)
Boiling point :666.8±55.0 °C(Predicted)
Density :1.32
storage temp. :-20°C Freezer
solubility :Methanol (Slightly)
pka :12.25±0.70(Predicted)
form :Solid
color :Off-White
Boiling point :666.8±55.0 °C(Predicted)
Density :1.32
storage temp. :-20°C Freezer
solubility :Methanol (Slightly)
pka :12.25±0.70(Predicted)
form :Solid
color :Off-White
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
Rebastinib is an orally bioavailable tyrosine kinase inhibitor that inhibits Abl1 (IC50 = 0.8 nM) as well as the gatekeeper mutant Abl1T315I (IC50 = 4 nM) and the activation loop mutant Abl1H396P. It also inhibits the Src family kinases Src, Lyn, Fgr, and Hck and the tyrosine kinases KDR, FLT3, and Tie2 at nanomolar concentrations. Rebastinib inhibits mutant Abl1T315I signaling and prolongs survival in a mouse Ba/F3 cell allograft model. Rebastinib also exhibits in vivo antineoplastic activity against cells with the T674I point mutation of FIP1-like-1-platelet-derived growth factor receptor α.More related product prices
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$1.00 /1KG
4-(4-(3-(3-(tert-Butyl)-1-(quinolin-6-yl)-1H-pyrazol-5-yl)ureido)-3-fluorophenoxy)-N-methylpicolinamide CAS:1020172-07-9
4-(4-(3-(3-(tert-Butyl)-1-(quinolin-6-yl)-1H-pyrazol-5-yl)ureido)-3-fluorophenoxy)-N-methylpicolinamide CAS:1020172-07-9