5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one
- $27 - $2691.1
- Product name: 5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one
- CAS: 1048371-03-4
- MF: C17H13NO3
- MW: 279.29
- EINECS:
- MDL Number:MFCD14051631
- Synonyms:5-(2-Oxo-2-phenylethoxy)-3,4-dihydroisoquinolin-1(2H)-one;UPF 1069;5-(2-Oxo-2-phenylethoxy)-1(2H)-isoquinolinone;1(2H)-Isoquinolinone, 5-(2-oxo-2-phenylethoxy)-;UPF 1069;UPF-1069; UPF1069;UPF 1069 10MG;UPF1069/UPF-1069;CS-874
32 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 10mM(in 1mL DMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 50mg
- 100mg
- 250mg
- 1g
- 1000mg
- ManufacturerAK Scientific
- Product number2785AH
- Product description5-Phenacyloxy-2H-isoquinolin-1-one
- Packaging2mg
- Price$113
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2785AH
- Product description5-Phenacyloxy-2H-isoquinolin-1-one
- Packaging5mg
- Price$142
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA906956
- Product descriptionUPF-1069 98+%
- Packaging1mg
- Price$27
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA906956
- Product descriptionUPF-1069 98+%
- Packaging5mg
- Price$53
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA906956
- Product descriptionUPF-1069 98+%
- Packaging10mg
- Price$91
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA906956
- Product descriptionUPF-1069 98+%
- Packaging50mg
- Price$235
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA906956
- Product descriptionUPF-1069 98+%
- Packaging100mg
- Price$306
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0001212
- Product descriptionUPF 1069 95.00%
- Packaging5MG
- Price$500.17
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4163
- Product descriptionUPF1069
- Packaging10mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4163
- Product descriptionUPF1069
- Packaging10mM(in 1mL DMSO)
- Price$99
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4163
- Product descriptionUPF1069
- Packaging50mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2369
- Product descriptionUPF1069 99%
- Packaging50mg
- Price$247.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180867
- Product descriptionUPF 1069 >98%
- Packaging100mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180867
- Product descriptionUPF 1069 >98%
- Packaging250mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180867
- Product descriptionUPF 1069 >98%
- Packaging1000mg
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17760
- Product descriptionUPF-1069 ≥98%
- Packaging50mg
- Price$381
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2785AH | 5-Phenacyloxy-2H-isoquinolin-1-one | 2mg | $113 | 2021-12-16 | Buy |
AK Scientific | 2785AH | 5-Phenacyloxy-2H-isoquinolin-1-one | 5mg | $142 | 2021-12-16 | Buy |
Ambeed | A906956 | UPF-1069 98+% | 1mg | $27 | 2021-12-16 | Buy |
Ambeed | A906956 | UPF-1069 98+% | 5mg | $53 | 2021-12-16 | Buy |
Ambeed | A906956 | UPF-1069 98+% | 10mg | $91 | 2021-12-16 | Buy |
Ambeed | A906956 | UPF-1069 98+% | 50mg | $235 | 2021-12-16 | Buy |
Ambeed | A906956 | UPF-1069 98+% | 100mg | $306 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0001212 | UPF 1069 95.00% | 5MG | $500.17 | 2021-12-16 | Buy |
ApexBio Technology | A4163 | UPF1069 | 10mg | $90 | 2021-12-16 | Buy |
ApexBio Technology | A4163 | UPF1069 | 10mM(in 1mL DMSO) | $99 | 2021-12-16 | Buy |
ApexBio Technology | A4163 | UPF1069 | 50mg | $290 | 2021-12-16 | Buy |
Axon Medchem | Axon2369 | UPF1069 99% | 50mg | $247.5 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180867 | UPF 1069 >98% | 100mg | $615.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180867 | UPF 1069 >98% | 250mg | $1208.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb180867 | UPF 1069 >98% | 1000mg | $2691.1 | 2021-12-16 | Buy |
Cayman Chemical | 17760 | UPF-1069 ≥98% | 50mg | $381 | 2024-03-01 | Buy |
Properties
storage temp. :Store at RT
solubility :Soluble in DMSO (up to 40 mg/ml).
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
solubility :Soluble in DMSO (up to 40 mg/ml).
form :solid
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
Safety Information
Symbol(GHS): | |||||||||||||||
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Signal word: | Warning | ||||||||||||||
Hazard statements: |
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Precautionary statements: |
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Description
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. UPF-1069 is a PARP inhibitor that demonstrates a modest preference for PARP2 over PARP1 (IC50s = 0.3 and 8 μM, respectively). In rat models of post-ischemic brain damage, it has been shown to increase cell death in hippocampal slice cultures in a model characterized by loss of neurons through a caspase-dependent, apoptosis-like process but to be protective of cortical neurons in a model characterized by a necrosis-like process.Related product price
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