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ChemicalBook >> CAS DataBase List >> 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine

5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine

5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine price.
  • $72 - $4725
  • Product name: 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
  • CAS: 1134156-31-2
  • MF: C25H23Cl2N7O4
  • MW: 556.4
  • EINECS:
  • MDL Number:MFCD18086892
  • Synonyms:VER 155008;4-((((2R,3S,4R,5R)-5-(6-aMino-8-((3,4-dichlorobenzyl)aMino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methoxy)Methyl)benzonitrile;8-(3,4-Dichlorobenzyl)aMino-5'-O-(4-cyanobenzyl)adenosine;4-{(2R,3S,4R,5R)-5-[6-aMino-8-(3,4-dichlorobenzylaMino)purin-9-yl]-3,4-dihydroxytetrahydrofuran-2-ylMethoxyMethyl}benzonitrile;VER 155088;5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine;VER-155008, ≥98% (HPLC);8-(3,4-Dichlorobenzyl)amino-5’-O-(4-cyanobenzyl)adenosine, VER155008
36 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
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  • 25mg
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  • 1g
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  • 10MG
  • 10G
  • 50MG
  • 5G
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product number2290AA
  • Product description5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine
  • Packaging1mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001088
  • Product descriptionVER 155008 99.00%
  • Packaging5MG
  • Price$206.8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001088
  • Product descriptionVER 155008 99.00%
  • Packaging10MG
  • Price$721.59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001088
  • Product descriptionVER 155008 99.00%
  • Packaging50MG
  • Price$1327.97
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001088
  • Product descriptionVER 155008 99.00%
  • Packaging5G
  • Price$3054.98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001088
  • Product descriptionVER 155008 99.00%
  • Packaging10G
  • Price$4498.73
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4387
  • Product descriptionVER155008
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4387
  • Product descriptionVER155008
  • Packaging10mM(in 1mL DMSO)
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1608
  • Product descriptionVER155008 99%
  • Packaging25mg
  • Price$363
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD144776
  • Product descriptionVER 155008
  • Packaging10mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD144776
  • Product descriptionVER 155008
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD144776
  • Product descriptionVER 155008
  • Packaging100mg
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD144776
  • Product descriptionVER 155008
  • Packaging250mg
  • Price$925
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD144776
  • Product descriptionVER 155008
  • Packaging500mg
  • Price$1435
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17257
  • Product descriptionVER-155008 ≥95%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17257
  • Product descriptionVER-155008 ≥95%
  • Packaging10mg
  • Price$176
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2290AA 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine 1mg $108 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001088 VER 155008 99.00% 5MG $206.8 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001088 VER 155008 99.00% 10MG $721.59 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001088 VER 155008 99.00% 50MG $1327.97 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001088 VER 155008 99.00% 5G $3054.98 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001088 VER 155008 99.00% 10G $4498.73 2021-12-16 Buy
ApexBio Technology A4387 VER155008 10mg $75 2021-12-16 Buy
ApexBio Technology A4387 VER155008 10mM(in 1mL DMSO) $85 2021-12-16 Buy
Axon Medchem Axon1608 VER155008 99% 25mg $363 2021-12-16 Buy
Biosynth Carbosynth FD144776 VER 155008 10mg $125 2021-12-16 Buy
Biosynth Carbosynth FD144776 VER 155008 50mg $300 2021-12-16 Buy
Biosynth Carbosynth FD144776 VER 155008 100mg $460 2021-12-16 Buy
Biosynth Carbosynth FD144776 VER 155008 250mg $925 2021-12-16 Buy
Biosynth Carbosynth FD144776 VER 155008 500mg $1435 2021-12-16 Buy
Cayman Chemical 17257 VER-155008 ≥95% 5mg $93 2024-03-01 Buy
Cayman Chemical 17257 VER-155008 ≥95% 10mg $176 2024-03-01 Buy

Properties

Boiling point :856.3±75.0 °C(Predicted)
Density :1.63±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >10mg/mL
pka :13.04±0.70(Predicted)
form :powder
color :white to light brown
InChIKey :ZXGGCBQORXDVTE-UMCMBGNQSA-N

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells.

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