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ChemicalBook >> CAS DataBase List >> N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide

N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide price.
  • $103 - $850
  • Product name: N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
  • CAS: 1135243-19-4
  • MF: C18H20N6O3S2
  • MW: 432.52
  • EINECS:
  • MDL Number:MFCD16875440
  • Synonyms:N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide;VU 0255035;N-(3-Oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonaMide;CID24768606;ML012;N-(3-oxo-3-(4-(pyridine-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide hydrate;N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide hydrate;VU0255035 hydrate
Price15 Properties Safety Information Description
15 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Crysdot
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5
  • 25
  • 5mg
  • 10mg
  • 25mg
  • 50MG
  • 1G
  • ManufacturerAK Scientific
  • Product number1354DC
  • Product descriptionN-(3-Oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide
  • Packaging10mg
  • Price$274
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001300
  • Product descriptionVU-0255035 99.00%
  • Packaging10MG
  • Price$404.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001300
  • Product descriptionVU-0255035 99.00%
  • Packaging50MG
  • Price$422.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001300
  • Product descriptionVU-0255035 99.00%
  • Packaging1G
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7487
  • Product descriptionVU0255035
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7487
  • Product descriptionVU0255035
  • Packaging25mg
  • Price$566
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19353
  • Product descriptionVU0255035 ≥98%
  • Packaging10mg
  • Price$158
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19353
  • Product descriptionVU0255035 ≥98%
  • Packaging50mg
  • Price$627
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004500
  • Product descriptionVU0255035 95+%
  • Packaging1g
  • Price$353
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberV3765
  • Product descriptionVU0255035 hydrate ≥98% (HPLC)
  • Packaging5mg
  • Price$155
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberV3765
  • Product descriptionVU0255035 hydrate ≥98% (HPLC)
  • Packaging25mg
  • Price$611
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3727
  • Product descriptionVU0255035 ≥99%(HPLC)
  • Packaging5
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3727
  • Product descriptionVU0255035 ≥99%(HPLC)
  • Packaging25
  • Price$389
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberV797685
  • Product descriptionVU0255035
  • Packaging25mg
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number257058
  • Product descriptionVU 0255035
  • Packaging10mg
  • Price$446
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1354DC N-(3-Oxo-3-(4-(pyridin-4-yl)piperazin-1-yl)propyl)benzo[c][1,2,5]thiadiazole-4-sulfonamide 10mg $274 2021-12-16 Buy
American Custom Chemicals Corporation INB0001300 VU-0255035 99.00% 10MG $404.5 2021-12-16 Buy
American Custom Chemicals Corporation INB0001300 VU-0255035 99.00% 50MG $422.5 2021-12-16 Buy
American Custom Chemicals Corporation INB0001300 VU-0255035 99.00% 1G $850 2021-12-16 Buy
ApexBio Technology B7487 VU0255035 5mg $150 2021-12-16 Buy
ApexBio Technology B7487 VU0255035 25mg $566 2021-12-16 Buy
Cayman Chemical 19353 VU0255035 ≥98% 10mg $158 2024-03-01 Buy
Cayman Chemical 19353 VU0255035 ≥98% 50mg $627 2024-03-01 Buy
Crysdot CD31004500 VU0255035 95+% 1g $353 2021-12-16 Buy
Sigma-Aldrich V3765 VU0255035 hydrate ≥98% (HPLC) 5mg $155 2024-03-01 Buy
Sigma-Aldrich V3765 VU0255035 hydrate ≥98% (HPLC) 25mg $611 2024-03-01 Buy
Tocris 3727 VU0255035 ≥99%(HPLC) 5 $103 2021-12-16 Buy
Tocris 3727 VU0255035 ≥99%(HPLC) 25 $389 2021-12-16 Buy
TRC V797685 VU0255035 25mg $360 2021-12-16 Buy
Usbiological 257058 VU 0255035 10mg $446 2021-12-16 Buy

Properties

Melting point :159.7-160.2 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3))
Boiling point :689.3±65.0 °C(Predicted)
Density :1.447±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: >5mg/mL
form :powder
pka :8.97±0.50(Predicted)
color :yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

VU0255035 is a competitive, orthosteric antagonist of the muscarinic M1 receptor (IC50 = 130 nM). It displays at least 75-fold selectivity for M1 over other muscarinic receptors, as well as a panel of receptors, ion channels, and transporters. VU0255035 is effective in cells and in vivo and brain penetrating, blocking pilocarpine-induced seizures without disrupting contextual fear conditioning in mice. VU0255035 is used to examine the role of the M1 receptor in diverse situations.

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