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ChemicalBook >> CAS DataBase List >> Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(diMethylaMino)-3-oxopropyl]thio]Methyl]thio]-, sodiuM salt, (E)-

Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(diMethylaMino)-3-oxopropyl]thio]Methyl]thio]-, sodiuM salt, (E)-

Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(diMethylaMino)-3-oxopropyl]thio]Methyl]thio]-, sodiuM salt, (E)- price.
  • $32 - $1800
  • Product name: Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(diMethylaMino)-3-oxopropyl]thio]Methyl]thio]-, sodiuM salt, (E)-
  • CAS: 115103-85-0
  • MF: C26H28ClN2NaO3S2
  • MW: 539.08
  • EINECS:
  • MDL Number:MFCD00878420
  • Synonyms:MK-571 SODIUM HYDRATE;Propanoic acid, 3-[[[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl][[3-(diMethylaMino)-3-oxopropyl]thio]Methyl]thio]-, sodiuM salt, (E)-;5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid sodium salt hydrate;MK-571 sodium salt hydrate;(E)-3-[[[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl][[3-(dimethylamino)-3-oxopropyl]thio]methyl]thio]propanoic acid sodium salt;MK-571 Sodium (L-660711);MK-571 sodium saL;L-660;711;MK571;MK 571;L660711;L-660711
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  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25MG
  • 50mg
  • 250mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-0021-M005
  • Product descriptionMK-571.sodiumsalt ≥97%(NMR)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9483CW
  • Product descriptionMK-571sodium
  • Packaging5mg
  • Price$167
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9483CW
  • Product descriptionMK-571sodium
  • Packaging50mg
  • Price$606
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000540
  • Product descriptionMK-571 SODIUM SALT HYDRATE 95.00%
  • Packaging5MG
  • Price$681.12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000540
  • Product descriptionMK-571 SODIUM SALT HYDRATE 95.00%
  • Packaging25MG
  • Price$963.53
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number70720
  • Product descriptionMK-571 (sodium salt) ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70720
  • Product descriptionMK-571 (sodium salt) ≥95%
  • Packaging5mg
  • Price$63
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number70720
  • Product descriptionMK-571 (sodium salt) ≥95%
  • Packaging10mg
  • Price$109
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number70720
  • Product descriptionMK-571 (sodium salt) ≥95%
  • Packaging50mg
  • Price$456
  • Updated2024-03-01
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  • ManufacturerChemScene
  • Product numberCS-5525
  • Product descriptionMK-571sodiumsalt 99.24%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5525
  • Product descriptionMK-571sodiumsalt 99.24%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5525
  • Product descriptionMK-571sodiumsalt 99.24%
  • Packaging25mg
  • Price$216
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-5525
  • Product descriptionMK-571sodiumsalt 99.24%
  • Packaging50mg
  • Price$384
  • Updated2021-12-16
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  • ManufacturerCSNpharm
  • Product numberCSN13506
  • Product descriptionMK-571Sodium
  • Packaging1mg
  • Price$37
  • Updated2021-12-16
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  • ManufacturerDC Chemicals
  • Product numberDC9279
  • Product descriptionMK-571 >98%
  • Packaging250mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9279
  • Product descriptionMK-571 >98%
  • Packaging1g
  • Price$1800
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CR1-0021-M005 MK-571.sodiumsalt ≥97%(NMR) 5mg $50 2021-12-16 Buy
AK Scientific 9483CW MK-571sodium 5mg $167 2021-12-16 Buy
AK Scientific 9483CW MK-571sodium 50mg $606 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000540 MK-571 SODIUM SALT HYDRATE 95.00% 5MG $681.12 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000540 MK-571 SODIUM SALT HYDRATE 95.00% 25MG $963.53 2021-12-16 Buy
Cayman Chemical 70720 MK-571 (sodium salt) ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 70720 MK-571 (sodium salt) ≥95% 5mg $63 2024-03-01 Buy
Cayman Chemical 70720 MK-571 (sodium salt) ≥95% 10mg $109 2024-03-01 Buy
Cayman Chemical 70720 MK-571 (sodium salt) ≥95% 50mg $456 2024-03-01 Buy
ChemScene CS-5525 MK-571sodiumsalt 99.24% 5mg $60 2021-12-16 Buy
ChemScene CS-5525 MK-571sodiumsalt 99.24% 10mg $96 2021-12-16 Buy
ChemScene CS-5525 MK-571sodiumsalt 99.24% 25mg $216 2021-12-16 Buy
ChemScene CS-5525 MK-571sodiumsalt 99.24% 50mg $384 2021-12-16 Buy
CSNpharm CSN13506 MK-571Sodium 1mg $37 2021-12-16 Buy
DC Chemicals DC9279 MK-571 >98% 250mg $900 2021-12-16 Buy
DC Chemicals DC9279 MK-571 >98% 1g $1800 2021-12-16 Buy

Properties

storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :H2O: soluble15mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The cysteinyl leukotrienes (CysLTs), LTC4, LTD4, and LTE4, mediate their actions through two distinct G protein-coupled receptors. LTD4 is the preferred ligand for the cysLT1 receptor, whereas LTC4 and LTD4 bind with approximately equal affinity to the CysLT2 receptor. MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively, which is indicative of CysLT1 receptor-mediated activity in these preparations. MK-571 effectively blocks LTD4 activation of recombinant human and mouse CysLT1 receptors but is ineffective at blocking LTC4 or LTD4 activation of the recombinant human or mouse CysLT2 receptors.