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ChemicalBook >> CAS DataBase List >> 4-oxo-27-TBDMS Withaferin A

4-oxo-27-TBDMS Withaferin A

4-oxo-27-TBDMS Withaferin A price.
  • $81 - $396
  • Product name: 4-oxo-27-TBDMS Withaferin A
  • CAS: 1214886-31-3
  • MF: C34H50O6Si
  • MW: 582.85
  • EINECS:
  • MDL Number:
  • Synonyms:4-oxo-27-TBDMS Withaferin A;Ergosta-2,24-dien-26-oic acid, 27-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,6-epoxy-22-hydroxy-1,4-dioxo-, δ-lactone, (5β,6β,22R)-;(5β,6β,22R)-27-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,6-epoxy-22-hydroxy-1,4-dioxo-ergosta-2,24-dien-26-oic acid, δ-lactone
Price3 Properties Safety Information Description
3 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerCayman Chemical
  • Product number28323
  • Product description4-oxo-27-TBDMS Withaferin A
  • Packaging1mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28323
  • Product description4-oxo-27-TBDMS Withaferin A
  • Packaging5mg
  • Price$238
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28323
  • Product description4-oxo-27-TBDMS Withaferin A
  • Packaging10mg
  • Price$396
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 28323 4-oxo-27-TBDMS Withaferin A 1mg $81 2024-03-01 Buy
Cayman Chemical 28323 4-oxo-27-TBDMS Withaferin A 5mg $238 2024-03-01 Buy
Cayman Chemical 28323 4-oxo-27-TBDMS Withaferin A 10mg $396 2024-03-01 Buy

Properties

Boiling point :651.3±55.0 °C(Predicted)
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5mg/mL

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 μM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 μM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.

Suppliers and manufacturers

TargetMol Chemicals Inc.
4-oxo-27-TBDMS Withaferin A
$198.00 /1mg
4-oxo-27-TBDMS Withaferin A CAS:1214886-31-3
Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. Changzhou Furuisi Biotechnology Co., Ltd Beijing Biocreative Technology Co., Ltd. Shanghai Yiyan Biotechnology Co. , Ltd. Shanghai Yifei Biotechnology Co. , Ltd. TargetMol Chemicals Inc.