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ChemicalBook >> CAS DataBase List >> 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-

6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-

$44 - $2520
Product name: 6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-
CAS: 1234479-76-5
MF: C25H29N7O2
MW: 459.54
EINECS:
MDL Number:MFCD18642659
Synonyms:6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-;ERK5-IN-1;XMD 8-85;ERK5-IN-1 XMD 8-85;CS-2049;ERK5 inhibitor 1;2-((2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-5,11-dimethyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one;ERK5 IN 1,ERK,Inhibitor,ERK-5-IN-1,Extracellular signal regulated kinases,ERK5IN1,inhibit

Price18 Properties Safety Information Description

18 prices

Selected condition：

Brand

AK Scientific
American Custom Chemicals Corporation
Apolloscientific
Cayman Chemical
ChemScene
Crysdot
Tocris

Package

10
1mg
5MG
10mg
25mg
50mg
100mg

ManufacturerAK Scientific
Product number8434DG
Product descriptionErk5-IN-1
Packaging50mg
Price$430
Updated2021-12-16
Buy

ManufacturerAmerican Custom Chemicals Corporation
Product numberCHM0292974
Product description5,11-DIHYDRO-2-[[2-METHOXY-4-(4-METHYL-1-PIPERAZINYL)PHENYL]AMINO]-5,11-DIMETHYL-6H-PYRIMIDO-[4,5-B]-[1,4]-BENZODIAZEPIN-6-ONE 95.00%
Packaging5MG
Price$496.76
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBISN0169
Product descriptionERK5-IN-1
Packaging1mg
Price$269
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBISN0169
Product descriptionERK5-IN-1
Packaging5mg
Price$493
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBISN0169
Product descriptionERK5-IN-1
Packaging10mg
Price$733
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number29662
Product descriptionXMD8-85
Packaging5mg
Price$44
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number29662
Product descriptionXMD8-85
Packaging10mg
Price$78
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number29662
Product descriptionXMD8-85
Packaging25mg
Price$172
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number29662
Product descriptionXMD8-85
Packaging50mg
Price$299
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-4938
Product descriptionERK5-IN-1 99.92%
Packaging5mg
Price$420
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-4938
Product descriptionERK5-IN-1 99.92%
Packaging10mg
Price$600
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-4938
Product descriptionERK5-IN-1 99.92%
Packaging50mg
Price$1800
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-4938
Product descriptionERK5-IN-1 99.92%
Packaging100mg
Price$2520
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31004153
Product descriptionERK5-IN-1 98+%
Packaging5mg
Price$243
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31004153
Product descriptionERK5-IN-1 98+%
Packaging10mg
Price$347
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31004153
Product descriptionERK5-IN-1 98+%
Packaging50mg
Price$1042
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
AK Scientific	8434DG	Erk5-IN-1	50mg	$430	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0292974	5,11-DIHYDRO-2-[[2-METHOXY-4-(4-METHYL-1-PIPERAZINYL)PHENYL]AMINO]-5,11-DIMETHYL-6H-PYRIMIDO-[4,5-B]-[1,4]-BENZODIAZEPIN-6-ONE 95.00%	5MG	$496.76	2021-12-16	Buy
Apolloscientific	BISN0169	ERK5-IN-1	1mg	$269	2021-12-16	Buy
Apolloscientific	BISN0169	ERK5-IN-1	5mg	$493	2021-12-16	Buy
Apolloscientific	BISN0169	ERK5-IN-1	10mg	$733	2021-12-16	Buy
Cayman Chemical	29662	XMD8-85	5mg	$44	2024-03-01	Buy
Cayman Chemical	29662	XMD8-85	10mg	$78	2024-03-01	Buy
Cayman Chemical	29662	XMD8-85	25mg	$172	2024-03-01	Buy
Cayman Chemical	29662	XMD8-85	50mg	$299	2024-03-01	Buy
ChemScene	CS-4938	ERK5-IN-1 99.92%	5mg	$420	2021-12-16	Buy
ChemScene	CS-4938	ERK5-IN-1 99.92%	10mg	$600	2021-12-16	Buy
ChemScene	CS-4938	ERK5-IN-1 99.92%	50mg	$1800	2021-12-16	Buy
ChemScene	CS-4938	ERK5-IN-1 99.92%	100mg	$2520	2021-12-16	Buy
Crysdot	CD31004153	ERK5-IN-1 98+%	5mg	$243	2021-12-16	Buy
Crysdot	CD31004153	ERK5-IN-1 98+%	10mg	$347	2021-12-16	Buy
Crysdot	CD31004153	ERK5-IN-1 98+%	50mg	$1042	2021-12-16	Buy

Next Last

Properties

Melting point :>136°C (dec.)
Boiling point :699.3±65.0 °C(Predicted)
Density :1.268±0.06 g/cm3(Predicted)
storage temp. :-20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly), Methanol (Slightly)
form :Solid
pka :7.75±0.42(Predicted)
color :Yellow to Dark Yellow

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ERK5-IN-1 is a potent selective ERK5 inhibitor, inhibiting EGFR-induced ERK5 autophosphorylation and ERK5 enzymatic activity. Orally bioavailable.

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6H-PyriMido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-Methoxy-4-(4-Methyl-1-piperazinyl)phenyl]aMino]-5,11-diMethyl-

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers