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ChemicalBook >> CAS DataBase List >> [S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride

[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride

[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride price.
  • $50 - $2200
  • Product name: [S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride
  • CAS: 1243259-19-9
  • MF: C12H26ClN3O2
  • MW: 279.81
  • EINECS:
  • MDL Number:MFCD11505486
  • Synonyms:(2S,3S)-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Hydrochloride;[S-(R*,R*)]-2-AMino-3-Methyl-N-[2-(4-Morpholinyl)ethyl]pentanaMide Dihydrochloride;(2S,3S)-2-AMINO-3-METHYL-N-(2-MORPHOLIN-4-YLETHYL)PENTANAMIDE;LM11A-31;Pentanamide, 2-amino-3-methyl-N-[2-(4-morpholinyl)ethyl]-, hydrochloride (1:2), (2S,3S)-;LM11A-31 (hydrochloride);(2S,3S)-2-Amino-3-methyl-N-(2-morpholinoethyl)pentanamide Dihydrochloride;LM11A-31 dihydrochloride (LM11A-31 BHS)
9 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 2.5g
  • ManufacturerAK Scientific
  • Product numberSYN5459
  • Product descriptionLM11A-31 dihydrochloride
  • Packaging50mg
  • Price$406
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21982
  • Product descriptionLM11A-31 (hydrochloride) ≥98%
  • Packaging5mg
  • Price$50
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21982
  • Product descriptionLM11A-31 (hydrochloride) ≥98%
  • Packaging10mg
  • Price$89
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21982
  • Product descriptionLM11A-31 (hydrochloride) ≥98%
  • Packaging25mg
  • Price$172
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21982
  • Product descriptionLM11A-31 (hydrochloride) ≥98%
  • Packaging50mg
  • Price$268
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC21242
  • Product descriptionLM11A-31 dihydrochloride >98%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC21242
  • Product descriptionLM11A-31 dihydrochloride >98%
  • Packaging250mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number49512
  • Product description(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamideHCl
  • Packaging2.5g
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA612500
  • Product description(2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamideHydrochloride
  • Packaging50mg
  • Price$90
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5459 LM11A-31 dihydrochloride 50mg $406 2021-12-16 Buy
Cayman Chemical 21982 LM11A-31 (hydrochloride) ≥98% 5mg $50 2024-03-01 Buy
Cayman Chemical 21982 LM11A-31 (hydrochloride) ≥98% 10mg $89 2024-03-01 Buy
Cayman Chemical 21982 LM11A-31 (hydrochloride) ≥98% 25mg $172 2024-03-01 Buy
Cayman Chemical 21982 LM11A-31 (hydrochloride) ≥98% 50mg $268 2024-03-01 Buy
DC Chemicals DC21242 LM11A-31 dihydrochloride >98% 100mg $550 2021-12-16 Buy
DC Chemicals DC21242 LM11A-31 dihydrochloride >98% 250mg $950 2021-12-16 Buy
Medical Isotopes, Inc. 49512 (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamideHCl 2.5g $2200 2021-12-16 Buy
TRC A612500 (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamideHydrochloride 50mg $90 2021-12-16 Buy

Properties

Melting point :>68°C (dec.)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 30 mg/ml)
form :solid
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

LM11A-31 is a p75 neurotrophin receptor (p75NTR) ligand that inhibits nerve growth factor (NGF) binding to p75NTR-Fc (A2 = 1,192 nM). It inhibits DNA damage in and promotes survival of hippocampal neuronal cultures in a p75NTR- and concentration-dependent manner. LMA11A-31 also inhibits proNGF-induced cell death of mature oligodendrocytes. In vivo, LMA11A-31 (10-100 mg/kg) improves motor function and coordination in the weight-bearing open-field test and nonweight-bearing swim test and increases survival of oligodendrocytes in a mouse model of spinal contusion injury. It prevents and/or reverses atrophy of forebrain cholinergic neurites and cortical dystrophic neurites in Thy-1 hAPPLond/Swe and Tg2576 mice with mid- to late stage Alzheimer''s disease. It also reduces excessive alcohol self-administration in rats and decreases huntingtin (Htt) aggregate formation and striatal cholinergic degeneration in the R6/2 mouse model of Huntington''s disease.

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