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ChemicalBook >> CAS DataBase List >> 5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE

5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE

5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE price.
  • $32 - $403
  • Product name: 5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE
  • CAS: 13027-33-3
  • MF: C27H46O3
  • MW: 418.65
  • EINECS:
  • MDL Number:MFCD00271438
  • Synonyms:5ALPHA-HYDROXY-6-KETO CHOLESTEROL;5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE;yakkasterone;3β,5-Dihydroxy-5α-cholestan-6-one;YS-64;5α-hydroxy-6-keto Cholesterol;CHOLESTANE-6-OXO-3,5-DIOL;CHOLESTANE-6-OXO-3BETA,5ALPHA-DIOL
Price7 Properties Safety Information Description
7 prices
Selected condition：
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • ManufacturerAK Scientific
  • Product number1446AH
  • Product description5alpha-Cholestan-3beta,5alpha-diol-6-one
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1446AH
  • Product description5alpha-Cholestan-3beta,5alpha-diol-6-one
  • Packaging10mg
  • Price$403
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007601
  • Product description5α-hydroxy-6-keto Cholesterol ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007601
  • Product description5α-hydroxy-6-keto Cholesterol ≥98%
  • Packaging5mg
  • Price$145
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10007601
  • Product description5α-hydroxy-6-keto Cholesterol ≥98%
  • Packaging10mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC432525
  • Product description5α-hydroxy-6-ketoCholesterol
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC432525
  • Product description5α-hydroxy-6-ketoCholesterol
  • Packaging2.5mg
  • Price$90
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1446AH 5alpha-Cholestan-3beta,5alpha-diol-6-one 1mg $133 2021-12-16 Buy
AK Scientific 1446AH 5alpha-Cholestan-3beta,5alpha-diol-6-one 10mg $403 2021-12-16 Buy
Cayman Chemical 10007601 5α-hydroxy-6-keto Cholesterol ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 10007601 5α-hydroxy-6-keto Cholesterol ≥98% 5mg $145 2024-03-01 Buy
Cayman Chemical 10007601 5α-hydroxy-6-keto Cholesterol ≥98% 10mg $275 2024-03-01 Buy
TRC C432525 5α-hydroxy-6-ketoCholesterol 1mg $45 2021-12-16 Buy
TRC C432525 5α-hydroxy-6-ketoCholesterol 2.5mg $90 2021-12-16 Buy

Properties

Melting point :234 °C
Boiling point :528.9±45.0 °C(Predicted)
Density :1.061±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 0.5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12?+-.0.70(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

5α-hydroxy-6-keto Cholesterol (6-oxo-3,5,-diol) is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone, with formation of 5β,6β-epoxycholesterol as a predominant precursor. Exposure of C57BL/6J mice to 0.5-3 ppm ozone produced a dose-dependent formation of 6-oxo-3,5,-diol which was detectable in the bronchalveolar lavage fluid, lavaged cells, and lung homogenates. 6-Oxo-3,5-diol is a potent inhibitor of cholesterol synthesis in human bronchial epithelial cells with an IC50 of 350 nM and exhibits significant cytotoxicity in the low μM range.

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