5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE
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- $32 - $403
- Product name: 5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE
- CAS: 13027-33-3
- MF: C27H46O3
- MW: 418.65
- EINECS:
- MDL Number:MFCD00271438
- Synonyms:5ALPHA-HYDROXY-6-KETO CHOLESTEROL;5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE;yakkasterone;3β,5-Dihydroxy-5α-cholestan-6-one;YS-64;5α-hydroxy-6-keto Cholesterol;CHOLESTANE-6-OXO-3,5-DIOL;CHOLESTANE-6-OXO-3BETA,5ALPHA-DIOL
7 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- TRC
Package
- 1mg
- 2.5mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number1446AH
- Product description5alpha-Cholestan-3beta,5alpha-diol-6-one
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1446AH
- Product description5alpha-Cholestan-3beta,5alpha-diol-6-one
- Packaging10mg
- Price$403
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10007601
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10007601
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging5mg
- Price$145
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10007601
- Product description5α-hydroxy-6-keto Cholesterol ≥98%
- Packaging10mg
- Price$275
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberC432525
- Product description5α-hydroxy-6-ketoCholesterol
- Packaging1mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberC432525
- Product description5α-hydroxy-6-ketoCholesterol
- Packaging2.5mg
- Price$90
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 1446AH | 5alpha-Cholestan-3beta,5alpha-diol-6-one | 1mg | $133 | 2021-12-16 | Buy |
AK Scientific | 1446AH | 5alpha-Cholestan-3beta,5alpha-diol-6-one | 10mg | $403 | 2021-12-16 | Buy |
Cayman Chemical | 10007601 | 5α-hydroxy-6-keto Cholesterol ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 10007601 | 5α-hydroxy-6-keto Cholesterol ≥98% | 5mg | $145 | 2024-03-01 | Buy |
Cayman Chemical | 10007601 | 5α-hydroxy-6-keto Cholesterol ≥98% | 10mg | $275 | 2024-03-01 | Buy |
TRC | C432525 | 5α-hydroxy-6-ketoCholesterol | 1mg | $45 | 2021-12-16 | Buy |
TRC | C432525 | 5α-hydroxy-6-ketoCholesterol | 2.5mg | $90 | 2021-12-16 | Buy |
Properties
Melting point :234 °C
Boiling point :528.9±45.0 °C(Predicted)
Density :1.061±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 0.5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12?+-.0.70(Predicted)
Boiling point :528.9±45.0 °C(Predicted)
Density :1.061±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 0.5 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12?+-.0.70(Predicted)
Safety Information
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Description
5α-hydroxy-6-keto Cholesterol (6-oxo-3,5,-diol) is a major metabolite of cholesterol formed during exposure of lung epithelial cells to ozone, with formation of 5β,6β-epoxycholesterol as a predominant precursor. Exposure of C57BL/6J mice to 0.5-3 ppm ozone produced a dose-dependent formation of 6-oxo-3,5,-diol which was detectable in the bronchalveolar lavage fluid, lavaged cells, and lung homogenates. 6-Oxo-3,5-diol is a potent inhibitor of cholesterol synthesis in human bronchial epithelial cells with an IC50 of 350 nM and exhibits significant cytotoxicity in the low μM range.More related product prices
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