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ChemicalBook >> CAS DataBase List >> S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid hydrate di(trifluoroacetate) salt

S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid hydrate di(trifluoroacetate) salt

S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid hydrate di(trifluoroacetate) salt price.
  • $73 - $2200
  • Product name: S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid hydrate di(trifluoroacetate) salt
  • CAS: 136676-91-0
  • MF: C33H33F3N4O5
  • MW: 622.65
  • EINECS:
  • MDL Number:MFCD08276969
  • Synonyms:(S)-1-[[4-(Dimethylamino)-3-methylphenyl]methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid bis(trifluoroacetate);PD 123319 bis(trifluoroacetate);PD 123,319 hydrate di(trifluoroacetate) salt;S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid hydrate di(trifluoroacetate) salt;PD 123,319 di(trifluoroacetate) salt hydrate;S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid di(trifluoroacetate) salt hydrate;PD 123319 (trifluoroacetate salt);PD123319; PD-123319; S-+-PD 123319
Price24 Properties Safety Information Description
24 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3957AH
  • Product descriptionPD 123,319 di(trifluoroacetate) salt hydrate
  • Packaging250mg
  • Price$996
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA424325
  • Product descriptionPD123319Ditrifluoroacetate 98+%
  • Packaging5mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA424325
  • Product descriptionPD123319Ditrifluoroacetate 98+%
  • Packaging10mg
  • Price$106
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000886
  • Product descriptionPD 123,319 DI(TRIFLUOROACETATE) SALT HYDRATE 95.00%
  • Packaging5MG
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000886
  • Product descriptionPD 123,319 DI(TRIFLUOROACETATE) SALT HYDRATE 95.00%
  • Packaging10MG
  • Price$836.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3704
  • Product descriptionPD123319ditrifluoroacetate
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3704
  • Product descriptionPD123319ditrifluoroacetate
  • Packaging10mg
  • Price$111
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3704
  • Product descriptionPD123319ditrifluoroacetate
  • Packaging25mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3704
  • Product descriptionPD123319ditrifluoroacetate
  • Packaging50mg
  • Price$353
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16099
  • Product descriptionPD 123319 (trifluoroacetate salt) ≥98%
  • Packaging5mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16099
  • Product descriptionPD 123319 (trifluoroacetate salt) ≥98%
  • Packaging10mg
  • Price$175
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16099
  • Product descriptionPD 123319 (trifluoroacetate salt) ≥98%
  • Packaging25mg
  • Price$385
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16099
  • Product descriptionPD 123319 (trifluoroacetate salt) ≥98%
  • Packaging50mg
  • Price$672
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM151440
  • Product description(S)-1-(4-(dimethylamino)-3-methylbenzyl)-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylicacidcompoundwith2,2,2-trifluoroaceticacid(1:2) 98%
  • Packaging50mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1547
  • Product descriptionPD123319ditrifluoroacetate 99.82%
  • Packaging5mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-1547
  • Product descriptionPD123319ditrifluoroacetate 99.82%
  • Packaging10mg
  • Price$144
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3957AH PD 123,319 di(trifluoroacetate) salt hydrate 250mg $996 2021-12-16 Buy
Ambeed A424325 PD123319Ditrifluoroacetate 98+% 5mg $73 2021-12-16 Buy
Ambeed A424325 PD123319Ditrifluoroacetate 98+% 10mg $106 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000886 PD 123,319 DI(TRIFLUOROACETATE) SALT HYDRATE 95.00% 5MG $550 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000886 PD 123,319 DI(TRIFLUOROACETATE) SALT HYDRATE 95.00% 10MG $836.8 2021-12-16 Buy
ApexBio Technology A3704 PD123319ditrifluoroacetate 5mg $90 2021-12-16 Buy
ApexBio Technology A3704 PD123319ditrifluoroacetate 10mg $111 2021-12-16 Buy
ApexBio Technology A3704 PD123319ditrifluoroacetate 25mg $232 2021-12-16 Buy
ApexBio Technology A3704 PD123319ditrifluoroacetate 50mg $353 2021-12-16 Buy
Cayman Chemical 16099 PD 123319 (trifluoroacetate salt) ≥98% 5mg $97 2024-03-01 Buy
Cayman Chemical 16099 PD 123319 (trifluoroacetate salt) ≥98% 10mg $175 2024-03-01 Buy
Cayman Chemical 16099 PD 123319 (trifluoroacetate salt) ≥98% 25mg $385 2024-03-01 Buy
Cayman Chemical 16099 PD 123319 (trifluoroacetate salt) ≥98% 50mg $672 2024-03-01 Buy
Chemenu CM151440 (S)-1-(4-(dimethylamino)-3-methylbenzyl)-5-(2,2-diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylicacidcompoundwith2,2,2-trifluoroaceticacid(1:2) 98% 50mg $243 2021-12-16 Buy
ChemScene CS-1547 PD123319ditrifluoroacetate 99.82% 5mg $115 2021-12-16 Buy
ChemScene CS-1547 PD123319ditrifluoroacetate 99.82% 10mg $144 2021-12-16 Buy
Next Last

Properties

storage temp. :2-8°C
solubility :H2O: soluble10mg/mL, clear
form :powder
color :White to yellow
Water Solubility :Soluble to 100 mM in water

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Angiotensin II is a peptide hormone that regulates blood pressure and fluid balance, contributing to hypertension, atherosclerosis, left ventricular hypertrophy, myocardial infarction, and heart failure. It binds with high affinity to two distinct receptors: AT1R (angiotensin type 1 receptor) and AT2R (angiotensin type 2 receptor). AT1R activation facilitates the ‘classical’ effects, including vasoconstriction, cellular growth, and proliferation, whereas AT2R activation offsets AT1R-mediated actions, promoting vasodilatation, apoptosis, and anti-growth effects. PD 123319 is a selective, nonpeptide AT2R antagonist (IC50 = 5.6 nM vs. 100 nM for AT1R). It has been used to selectively examine the specific roles for AT1R and AT2R in hypertensive and other vascular research-related models.

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Suppliers and manufacturers

career henan chemical co
S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid hydrate di(trifluoroacetate) salt
$9.80 /1.79999995231628KG
S-(+)-1-[(4-(Dimethylamino)-3-methylphenyl)methyl]-5-(diphenylacetyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid hydrate di(trifluoroacetate) salt CAS:136676-91-0
ATK CHEMICAL COMPANY LIMITED
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
InvivoChem
LEAPCHEM CO., LTD.
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
Amadis Chemical Company Limited Haoyuan Chemexpress Co., Ltd.