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ChemicalBook >> CAS DataBase List >> 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester

5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester price.
  • $57 - $1055
  • Product name: 5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester
  • CAS: 1416324-85-0
  • MF: C19H22O7
  • MW: 362.37
  • EINECS:
  • MDL Number:MFCD26406409
  • Synonyms:5H-Benzocycloheptene-8-carboxylic acid, 3,4,6-trihydroxy-2-methoxy-5-oxo-, hexyl ester;CU-CPT22;hexyl 3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate;3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester;CU-CPT22 >=98% (HPLC);inhibit,CU CPT22,Inhibitor,CU-CPT22,Toll-like Receptor (TLR),CUCPT22,CU-CPT-22
15 prices
Selected condition:
Brand
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Tocris
  • TRC
Package
  • 1mg
  • 10mg
  • 10
  • 5mg
  • 50
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAmbeed
  • Product numberA707204
  • Product descriptionHexyl3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate 97%
  • Packaging25mg
  • Price$382
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA707204
  • Product descriptionHexyl3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate 97%
  • Packaging50mg
  • Price$569
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA707204
  • Product descriptionHexyl3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate 97%
  • Packaging100mg
  • Price$851
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5753
  • Product descriptionCUCPT22
  • Packaging5mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5753
  • Product descriptionCUCPT22
  • Packaging10mg
  • Price$299
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5753
  • Product descriptionCUCPT22
  • Packaging25mg
  • Price$583
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15244
  • Product descriptionCU CPT 22
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15244
  • Product descriptionCU CPT 22
  • Packaging5mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15244
  • Product descriptionCU CPT 22
  • Packaging10mg
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0028870
  • Product descriptionCU-CPT22 >99.0%
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0028870
  • Product descriptionCU-CPT22 >99.0%
  • Packaging10mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0028870
  • Product descriptionCU-CPT22 >99.0%
  • Packaging25mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4884
  • Product descriptionCUCPT22 ≥98%(HPLC)
  • Packaging10
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4884
  • Product descriptionCUCPT22 ≥98%(HPLC)
  • Packaging50
  • Price$1055
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberC852003
  • Product descriptionCUCPT22
  • Packaging1mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A707204 Hexyl3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate 97% 25mg $382 2021-12-16 Buy
Ambeed A707204 Hexyl3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate 97% 50mg $569 2021-12-16 Buy
Ambeed A707204 Hexyl3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate 97% 100mg $851 2021-12-16 Buy
ApexBio Technology B5753 CUCPT22 5mg $189 2021-12-16 Buy
ApexBio Technology B5753 CUCPT22 10mg $299 2021-12-16 Buy
ApexBio Technology B5753 CUCPT22 25mg $583 2021-12-16 Buy
Cayman Chemical 15244 CU CPT 22 1mg $57 2024-03-01 Buy
Cayman Chemical 15244 CU CPT 22 5mg $152 2024-03-01 Buy
Cayman Chemical 15244 CU CPT 22 10mg $275 2024-03-01 Buy
ChemScene CS-0028870 CU-CPT22 >99.0% 5mg $130 2021-12-16 Buy
ChemScene CS-0028870 CU-CPT22 >99.0% 10mg $220 2021-12-16 Buy
ChemScene CS-0028870 CU-CPT22 >99.0% 25mg $420 2021-12-16 Buy
Tocris 4884 CUCPT22 ≥98%(HPLC) 10 $266 2021-12-16 Buy
Tocris 4884 CUCPT22 ≥98%(HPLC) 50 $1055 2021-12-16 Buy
TRC C852003 CUCPT22 1mg $160 2021-12-16 Buy

Properties

Boiling point :610.4±55.0 °C(Predicted)
Density :1.336±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :6.04±0.20(Predicted)
form :Powder
color :orange to dark red

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P273 Avoid release to the environment.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P501 Dispose of contents/container to..…

Description

CU CPT 22 is an antagonist of toll-like receptor 1 (TLR1) and TLR2 heterodimers (TLR1/TLR2; Ki = 0.41 μM). It inhibits nitric oxide (NO) production induced by the TLR2 agonist Pam3CSK4 in RAW 264.7 cells (IC50 = 0.58 μM). It is selective for TLR1/TLR2 over TLR2/TLR6 and TLR3, -4, and -7 homodimers, as well as 10 kinases at 0.5 μM. CU CPT 22 (8 μM) inhibits Pam3CSK4-induced release of TNF-α and IL-1β in RAW 264.7 cells by 60 and 95%, respectively.