(R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone
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- $129 - $517
- Product name: (R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone
- CAS: 150627-37-5
- MF: C21H36O5
- MW: 368.51
- EINECS:
- MDL Number:MFCD20488046
- Synonyms:(R)-3-Hexadecanoyl-5-hydroxymethyltetronic acid;(R)-4-Hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone;RK-682 >=98% (HPLC);2(5H)-Furanone, 4-hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-, (5R)-
2 prices
Selected condition：
Brand
- Sigma-Aldrich
Package
- 200μg
- 1mg
- ManufacturerSigma-Aldrich
- Product numberR2033
- Product descriptionRK-682 ≥98% (HPLC)
- Packaging1mg
- Price$517
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberR2033
- Product descriptionRK-682 ≥98%(HPLC)
- Packaging200μg
- Price$129
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Sigma-Aldrich | R2033 | RK-682 ≥98% (HPLC) | 1mg | $517 | 2024-03-01 | Buy |
| Sigma-Aldrich | R2033 | RK-682 ≥98%(HPLC) | 200μg | $129 | 2024-03-01 | Buy |
Properties
Melting point :105-107 °C
Boiling point :546.7±50.0 °C(Predicted)
Density :1.073±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO, heptane and xylene: ≥8mg/mL
pka :1.80±0.10(Predicted)
form :powder
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :546.7±50.0 °C(Predicted)
Density :1.073±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO, heptane and xylene: ≥8mg/mL
pka :1.80±0.10(Predicted)
form :powder
color :white to tan
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
(±)-RK-682 (150627-37-5) is a protein tyrosine phosphatase inhibitor (IC50‘s = 54 7 μM for CD45, 2.0 μM for VHR; did not inhibit cdc25B) originally isolated from the fermentation of Streptomyces sp. 88-682.1?Inhibits cell cycle at G1/S. RK-682 has also been shown to inhibit PLA2 (IC50?= 16 μM)2, HIV-1 protease (IC50?= 84 μlM)3, and heparanase (IC50?= 17 μM)4. Natural RK-682 (R-isomer) and synthetic racemic material have identical phosphatase activity.5?Care should be taken when using RK-682 in the presence of metal salts – because it readily forms metal complexes that affects its phosphatase inhibitory activity.6?RK-682 has been identified as a potential promiscuous inhibitor.7Related product price
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