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ChemicalBook >> CAS DataBase List >> 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride

2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride

2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride price.
  • $37 - $1344
  • Product name: 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride
  • CAS: 177172-49-5
  • MF: C18H23Cl2NO
  • MW: 340.28732
  • EINECS:
  • MDL Number:MFCD16038895
  • Synonyms:2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride;R 568 hydrochloride;Tecalcet (Hydrochloride);R-568;Tecalcet HCl (KRN568;NPS-R568;R-568 hydrochloride >=95% (HPLC);Benzenepropanamine, 2-chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-, hydrochloride (1:1)
19 prices
Selected condition:
Brand
  • AK Scientific
  • Alichem
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 1mg
  • 50
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number0855CB
  • Product descriptionTecalcethydrochloride
  • Packaging5mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number177172495
  • Product description(R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride
  • Packaging100mg
  • Price$320
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number177172495
  • Product description(R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride
  • Packaging250mg
  • Price$522.24
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number177172495
  • Product description(R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride
  • Packaging1g
  • Price$1344
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7504
  • Product descriptionR568hydrochloride
  • Packaging5mg
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7504
  • Product descriptionR568hydrochloride
  • Packaging10mg
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7504
  • Product descriptionR568hydrochloride
  • Packaging50mg
  • Price$804
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17415
  • Product descriptionR-568 ≥98%
  • Packaging50mg
  • Price$704
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17415
  • Product descriptionR-568 ≥98%
  • Packaging10mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17415
  • Product descriptionR-568 ≥98%
  • Packaging5mg
  • Price$90
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17415
  • Product descriptionR-568 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0002492
  • Product descriptionTecalcet(Hydrochloride) 99.66%
  • Packaging5mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0002492
  • Product descriptionTecalcet(Hydrochloride) 99.66%
  • Packaging10mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12131955
  • Product description(R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride 95%
  • Packaging10mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD12131955
  • Product description(R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride 95%
  • Packaging100mg
  • Price$405
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3815
  • Product descriptionR568hydrochloride ≥99%(HPLC)
  • Packaging10
  • Price$166
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 0855CB Tecalcethydrochloride 5mg $198 2021-12-16 Buy
Alichem 177172495 (R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride 100mg $320 2021-12-16 Buy
Alichem 177172495 (R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride 250mg $522.24 2021-12-16 Buy
Alichem 177172495 (R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride 1g $1344 2021-12-16 Buy
ApexBio Technology B7504 R568hydrochloride 5mg $102 2021-12-16 Buy
ApexBio Technology B7504 R568hydrochloride 10mg $182 2021-12-16 Buy
ApexBio Technology B7504 R568hydrochloride 50mg $804 2021-12-16 Buy
Cayman Chemical 17415 R-568 ≥98% 50mg $704 2024-03-01 Buy
Cayman Chemical 17415 R-568 ≥98% 10mg $161 2024-03-01 Buy
Cayman Chemical 17415 R-568 ≥98% 5mg $90 2024-03-01 Buy
Cayman Chemical 17415 R-568 ≥98% 1mg $37 2024-03-01 Buy
ChemScene CS-0002492 Tecalcet(Hydrochloride) 99.66% 5mg $80 2021-12-16 Buy
ChemScene CS-0002492 Tecalcet(Hydrochloride) 99.66% 10mg $130 2021-12-16 Buy
Crysdot CD12131955 (R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride 95% 10mg $127 2021-12-16 Buy
Crysdot CD12131955 (R)-3-(2-Chlorophenyl)-N-(1-(3-methoxyphenyl)ethyl)propan-1-aminehydrochloride 95% 100mg $405 2021-12-16 Buy
Tocris 3815 R568hydrochloride ≥99%(HPLC) 10 $166 2021-12-16 Buy

Properties

Melting point :183.3-184.4 °C
storage temp. :Inert atmosphere,Room Temperature
solubility :DMSO : 50 mg/mL (146.93 mM; Need ultrasonic)
form :Powder
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is involved in calcium homeostasis. Activation of CaSR on parathyroid cells decreases the secretion of parathyroid hormone (PTH), which in turn reduces blood calcium concentration. R-568 is a calcimimetic compound that can allosterically activate or positively modulate the human CaSR. It dose-dependently decreases circulating levels of PTH in both normal individuals and patients with primary hyperparathyroidism in clinical trials. R-568 is used in research to explore novel actions of CaSR.