4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide
![4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide price.](/CAS/GIF/188591-46-0.gif)
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- $47 - $8326
- Product name: 4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide
- CAS: 188591-46-0
- MF: C15H12ClF3N2O3S
- MW: 392.78
- EINECS:
- MDL Number:MFCD00099612
- Synonyms:4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide;GSK 3787;GSK3787/GSK-3787;Benzamide, 4-chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-;4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-benzamide GSK 3787;4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide;4-chloro-N-(2-(5-(trifluoromethyl)pyridin-2-ylsulfonyl)ethyl)benzamide;GSK3787;GSK 3787;GSK-3787
29 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 5mg
- 10mg
- 10
- 25mg
- 50mg
- 100mg
- 10mM(in 1mL DMSO)
- 250mg
- 1g
- 5g
- ManufacturerAK Scientific
- Product numberY0453
- Product description4-Chloro-N-[2-[[5-(trifluoromethyl-2-pyridinyl]sulfonyl]ethyl]benzamide
- Packaging25mg
- Price$224
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA575893
- Product descriptionGSK3787 98+%
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA575893
- Product descriptionGSK3787 98+%
- Packaging10mg
- Price$155
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA575893
- Product descriptionGSK3787 98+%
- Packaging25mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA575893
- Product descriptionGSK3787 98+%
- Packaging50mg
- Price$348
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA575893
- Product descriptionGSK3787 98+%
- Packaging100mg
- Price$521
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA575893
- Product descriptionGSK3787 98+%
- Packaging250mg
- Price$833
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0000021
- Product descriptionGSK3787 95.00%
- Packaging10MG
- Price$710.33
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberMTB0000021
- Product descriptionGSK3787 95.00%
- Packaging50MG
- Price$1056.83
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4303
- Product descriptionGSK3787
- Packaging10mM(in 1mL DMSO)
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15219
- Product descriptionGSK3787 ≥95%
- Packaging5mg
- Price$47
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15219
- Product descriptionGSK3787 ≥95%
- Packaging10mg
- Price$73
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15219
- Product descriptionGSK3787 ≥95%
- Packaging25mg
- Price$160
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15219
- Product descriptionGSK3787 ≥95%
- Packaging50mg
- Price$250
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM176447
- Product description4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide 98%
- Packaging50mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1262
- Product descriptionGSK3787 99.04%
- Packaging10mg
- Price$106
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y0453 | 4-Chloro-N-[2-[[5-(trifluoromethyl-2-pyridinyl]sulfonyl]ethyl]benzamide | 25mg | $224 | 2021-12-16 | Buy |
| Ambeed | A575893 | GSK3787 98+% | 5mg | $104 | 2021-12-16 | Buy |
| Ambeed | A575893 | GSK3787 98+% | 10mg | $155 | 2021-12-16 | Buy |
| Ambeed | A575893 | GSK3787 98+% | 25mg | $232 | 2021-12-16 | Buy |
| Ambeed | A575893 | GSK3787 98+% | 50mg | $348 | 2021-12-16 | Buy |
| Ambeed | A575893 | GSK3787 98+% | 100mg | $521 | 2021-12-16 | Buy |
| Ambeed | A575893 | GSK3787 98+% | 250mg | $833 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000021 | GSK3787 95.00% | 10MG | $710.33 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0000021 | GSK3787 95.00% | 50MG | $1056.83 | 2021-12-16 | Buy |
| ApexBio Technology | A4303 | GSK3787 | 10mM(in 1mL DMSO) | $97 | 2021-12-16 | Buy |
| Cayman Chemical | 15219 | GSK3787 ≥95% | 5mg | $47 | 2024-03-01 | Buy |
| Cayman Chemical | 15219 | GSK3787 ≥95% | 10mg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 15219 | GSK3787 ≥95% | 25mg | $160 | 2024-03-01 | Buy |
| Cayman Chemical | 15219 | GSK3787 ≥95% | 50mg | $250 | 2024-03-01 | Buy |
| Chemenu | CM176447 | 4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide 98% | 50mg | $226 | 2021-12-16 | Buy |
| ChemScene | CS-1262 | GSK3787 99.04% | 10mg | $106 | 2021-12-16 | Buy |
Properties
Boiling point :585.1±50.0 °C(Predicted)
Density :1.448±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :12.92±0.46(Predicted)
form :White solid
color :white to off-white
Stability :Stable for 1 year for up to year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :188591-46-0
Density :1.448±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :DMSO: ≥10mg/mL
pka :12.92±0.46(Predicted)
form :White solid
color :white to off-white
Stability :Stable for 1 year for up to year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
CAS DataBase Reference :188591-46-0
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
PPARβ/δ is thought to play a role in lipid homeostasis and glucose disposal by regulating genes involved in fatty acid oxidation, reverse cholesterol transport, and carbon substrate utilization in skeletal muscle. It has also been implicated in the progression of certain cancers. GSK3787 is an irreversible antagonist of PPARβ/δ (pIC50 = 6.6) with no measurable affinity for PPARα or PPARγ (pIC50 >5). At 1μM, it inhibits the expression of PPARβ/δ-regulated target genes, pyruvate dehydrogenase kinase 4 and carnitine palmitoyl transferase 1a, which are important for energy homeostasis in human skeletal muscle cells. GSK3787 (at 1 μM) also antagonizes agonist-induced expression of angiopoietin-like protein 4 in mouse fibroblasts, mouse keratinocytes, and human MCF-7, Huh7, and HepG2 cancer cell lines.More related product prices
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Suppliers and manufacturers
career henan chemical co
![4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide](https://img.chemicalbook.com/ProductImageEN/2019-12/small/414b4823-7efc-4873-bf22-2facb1451d14.png)
ATK CHEMICAL COMPANY LIMITED
Hubei Jusheng Technology Co.,Ltd.
Changzhou PBpharmaceutical R&D Co.,Ltd
BOC Sciences
TargetMol Chemicals Inc.
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited
Dayang Chem (Hangzhou) Co.,Ltd.
Zhejiang J&C Biological Technology Co.,Limited
$9.80 /1.79999995231628KG
4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide CAS:188591-46-0
4-Chloro-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]benzamide CAS:188591-46-0