BGC 20-1531 (hydrochloride)
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- $32 - $471
- Product name: BGC 20-1531 (hydrochloride)
- CAS: 1962928-26-2
- MF: C26H25ClN2O6S
- MW: 529
- EINECS:
- MDL Number:MFCD30182277
- Synonyms:BGC 20-1531 (hydrochloride);AP 1531;BGC20-1531 (PGN-1531;4-[[4-(5-Methoxy-2-pyridinyl)phenoxy]methyl]-5-methyl-N-[(2-methylphenyl)sulfonyl]-2-furancarboxamide hydrochloride;GTPL3380 hydrochloride;AP-1531 hydrochloride;BGC201531 hydrochloride(1186532615 free base),BGC 20 1531 hydrochloride(1186532 61 5 free base)
7 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Tocris
- TRC
Package
- 10
- 500μg
- 1mg
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number6151EG
- Product description4-[[4-(5-Methoxypyridin-2-yl)phenoxy]methyl]-5-methyl-N-(2-methylphenyl)sulfonylfuran-2-carboxamide;hydrochloride
- Packaging10mg
- Price$471
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19742
- Product descriptionBGC 20-1531 (hydrochloride) ≥98%
- Packaging500μg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19742
- Product descriptionBGC 20-1531 (hydrochloride) ≥98%
- Packaging1mg
- Price$50
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19742
- Product descriptionBGC 20-1531 (hydrochloride) ≥98%
- Packaging5mg
- Price$214
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19742
- Product descriptionBGC 20-1531 (hydrochloride) ≥98%
- Packaging10mg
- Price$335
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number5327
- Product descriptionBGC20-1531hydrochloride ≥98%(HPLC)
- Packaging10
- Price$332
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB366753
- Product descriptionBGC20-1531Hydrochloride
- Packaging1mg
- Price$195
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6151EG | 4-[[4-(5-Methoxypyridin-2-yl)phenoxy]methyl]-5-methyl-N-(2-methylphenyl)sulfonylfuran-2-carboxamide;hydrochloride | 10mg | $471 | 2021-12-16 | Buy |
| Cayman Chemical | 19742 | BGC 20-1531 (hydrochloride) ≥98% | 500μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19742 | BGC 20-1531 (hydrochloride) ≥98% | 1mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 19742 | BGC 20-1531 (hydrochloride) ≥98% | 5mg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 19742 | BGC 20-1531 (hydrochloride) ≥98% | 10mg | $335 | 2024-03-01 | Buy |
| Tocris | 5327 | BGC20-1531hydrochloride ≥98%(HPLC) | 10 | $332 | 2021-12-16 | Buy |
| TRC | B366753 | BGC20-1531Hydrochloride | 1mg | $195 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml
form :A crystalline solid
solubility :DMF: 1 mg/ml; DMSO: 1 mg/ml
form :A crystalline solid
Safety Information
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Description
BGC 20-1531 is a potent and selective antagonist of the prostaglandin E2 (PGE2; ) receptor subtype 4 (EP4) with Ki values of 11.7, >10,000, and >10,000 nM for EP4, EP2, and EP3, respectively. It is selective for EP4, exhibiting <50% inhibition at 47 ion channels, cell-surface transporters, enzymes, and nuclear receptors at a concentration of 10 μM. BGC 20-1531 antagonizes PGE2-induced cAMP accumulation in a dose-dependent manner in HEK293 EBNA cells that stably express human EP4 receptors. It also reverses PGE2-induced vasorelaxation (Kb = 15.85 nM) in human middle cerebral and middle meningeal arterial rings. BGC 20-1531 prevents PGE2-induced increases in carotid blood flow and decreases in carotid resistance with an ID50 value of 5 mg/kg in dogs.Suppliers and manufacturers
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Hongye Biotechnology Co. Ltd
Shanghai Luofa Biochemical Technology Co., Ltd.
