3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-
![3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo- price.](/CAS/GIF/209342-40-5.gif)
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- $102 - $3691
- Product name: 3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-
- CAS: 209342-40-5
- MF: C20H19FN4O4
- MW: 398.39
- EINECS:
- MDL Number:MFCD13185157
- Synonyms:3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-;Finafloxacin;BAY35-3377,finafloxacin hydrochloride;8-cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid;Finafloxacin (BAY35-3377);100827;(-)-(4aS,7aS)-8-Cyano-1-cyclopropyl-6-fluoro-4-oxo-7-(perhydropyrrolo[3,4-b]-1,4-oxazin-6-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
18 prices
Selected condition：
Brand
- AK Scientific
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number9092CS
- Product descriptionFinafloxacin
- Packaging10mg
- Price$1805
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM146295
- Product description8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 98%
- Packaging100mg
- Price$1374
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5557
- Product descriptionFinafloxacin 99.88%
- Packaging1mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5557
- Product descriptionFinafloxacin 99.88%
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5557
- Product descriptionFinafloxacin 99.88%
- Packaging10mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5557
- Product descriptionFinafloxacin 99.88%
- Packaging50mg
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5557
- Product descriptionFinafloxacin 99.88%
- Packaging100mg
- Price$2520
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002710
- Product descriptionFinafloxacin 98+%
- Packaging5mg
- Price$245
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002710
- Product descriptionFinafloxacin 98+%
- Packaging10mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002710
- Product descriptionFinafloxacin 98+%
- Packaging50mg
- Price$1050
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31002710
- Product descriptionFinafloxacin 98+%
- Packaging100mg
- Price$1470
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8847
- Product descriptionFinafloxacin(BAY35-3377) >98%
- Packaging10mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8847
- Product descriptionFinafloxacin(BAY35-3377) >98%
- Packaging25mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8847
- Product descriptionFinafloxacin(BAY35-3377) >98%
- Packaging100mg
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number143683
- Product description8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95%
- Packaging2mg
- Price$1841
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number143683
- Product description8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95%
- Packaging5mg
- Price$3691
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9092CS | Finafloxacin | 10mg | $1805 | 2021-12-16 | Buy |
| Chemenu | CM146295 | 8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylicacid 98% | 100mg | $1374 | 2021-12-16 | Buy |
| ChemScene | CS-5557 | Finafloxacin 99.88% | 1mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-5557 | Finafloxacin 99.88% | 5mg | $420 | 2021-12-16 | Buy |
| ChemScene | CS-5557 | Finafloxacin 99.88% | 10mg | $600 | 2021-12-16 | Buy |
| ChemScene | CS-5557 | Finafloxacin 99.88% | 50mg | $1800 | 2021-12-16 | Buy |
| ChemScene | CS-5557 | Finafloxacin 99.88% | 100mg | $2520 | 2021-12-16 | Buy |
| Crysdot | CD31002710 | Finafloxacin 98+% | 5mg | $245 | 2021-12-16 | Buy |
| Crysdot | CD31002710 | Finafloxacin 98+% | 10mg | $350 | 2021-12-16 | Buy |
| Crysdot | CD31002710 | Finafloxacin 98+% | 50mg | $1050 | 2021-12-16 | Buy |
| Crysdot | CD31002710 | Finafloxacin 98+% | 100mg | $1470 | 2021-12-16 | Buy |
| DC Chemicals | DC8847 | Finafloxacin(BAY35-3377) >98% | 10mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC8847 | Finafloxacin(BAY35-3377) >98% | 25mg | $900 | 2021-12-16 | Buy |
| DC Chemicals | DC8847 | Finafloxacin(BAY35-3377) >98% | 100mg | $1800 | 2021-12-16 | Buy |
| Matrix Scientific | 143683 | 8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% | 2mg | $1841 | 2021-12-16 | Buy |
| Matrix Scientific | 143683 | 8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 95% | 5mg | $3691 | 2021-12-16 | Buy |
Properties
Boiling point :686.2±55.0 °C(Predicted)
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : 6.4 mg/mL (16.06 mM)
pka :6.38±0.50(Predicted)
form :powder
color :white to beige
Density :1.57±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO : 6.4 mg/mL (16.06 mM)
pka :6.38±0.50(Predicted)
form :powder
color :white to beige
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Finafloxacin, an antimicrobial agent of the 8-cyano subclass of fluoroquinolones, was approved by the US FDA in December 2014 for treatment of acute otitis externa, commonly known as swimmer’s ear, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus. Finafloxacin was developed by MerLion Pharmaceuticals in partnership with Bayer Health Care Pharmaceuticals, and the drug was licensed by Mer- Lion to Alcon (a division of Novartis) for development and commercialization for ear infections in North America. In contrast to other marketed fluoroquinolones, which display reduced activity in slightly acidic environments, finafloxacin exhibits increased antibacterial activity at pH 5–6, with minimum inhibitory concentration values that are 4- to 8-fold lower than at neutral pH. It is highly selective for bacterial type II topoisomerases, which are involved in bacterial DNA replication, transcription, repair, and recombination, and has broad spectrum antibacterial activity against Gram-positive and Gram-negative strains, including ciprofloxacin-resistant strains.More related product prices
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$49-1208.7 - Sucralfate
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![3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-](https://img.chemicalbook.com/ProductImageEN/2019-7/small/245eb5c8-6603-4eaf-ae9d-1eebc21e1716.jpg){kind=small}