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ChemicalBook >> CAS DataBase List >> 1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione price.
  • $29 - $1601
  • Product name: 1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione
  • CAS: 2108603-03-6
  • MF: C27H23F3N2O5S
  • MW: 544.54
  • EINECS:
  • MDL Number:
  • Synonyms:1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione;CAY10406,CAY-10406;1H-Indole-2,3-dione, 1-(phenylmethyl)-5-[[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]-1-pyrrolidinyl]sulfonyl]-;(S)-1-benzyl-5-(1-[2-(phenoxy-p-trifluoromethyl)-pyrrolidynyl]-sulfonyl)-isatin;CAY10406, Putative caspase 3 and 7 inhibitor
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • 100mg
  • ManufacturerCayman Chemical
  • Product number72510
  • Product descriptionCAY10406
  • Packaging1mg
  • Price$29
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number72510
  • Product descriptionCAY10406
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number72510
  • Product descriptionCAY10406
  • Packaging10mg
  • Price$216
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number72510
  • Product descriptionCAY10406
  • Packaging100mg
  • Price$1601
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 72510 CAY10406 1mg $29 2024-03-01 Buy
Cayman Chemical 72510 CAY10406 5mg $121 2024-03-01 Buy
Cayman Chemical 72510 CAY10406 10mg $216 2024-03-01 Buy
Cayman Chemical 72510 CAY10406 100mg $1601 2024-03-01 Buy

Properties

Boiling point :692.2±65.0 °C(Predicted)
Density :1.427±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.5 mg/ml; DMSO: 10 mg/ml; Ethanol: .05 mg/ml
form :A crystalline solid
pka :-6.05±0.20(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits Ki values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are ''effector caspases'' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406.

Suppliers and manufacturers

TargetMol Chemicals Inc.
CAY10406
$73.00 /1mg
CAY10406 CAS:2108603-03-6
Shanghai Hongye Biotechnology Co. Ltd TargetMol Chemicals Inc. Shanghai Yiyan Biotechnology Co. , Ltd. Shanghai Yifei Biotechnology Co. , Ltd.