ChemicalBook >> CAS DataBase List >>1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione structure

CAS No.: 2108603-03-6

Chemical Name:: 1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

Synonyms: CAY10406,CAY-10406;(S)-1-benzyl-5-(1-[2-(phenoxy-p-trifluoromethyl)-pyrrolidynyl]-sulfonyl)-isatin;1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione;1H-Indole-2,3-dione, 1-(phenylmethyl)-5-[[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]-1-pyrrolidinyl]sulfonyl]-

CBNumber:: CB83858099

Molecular Formula:: C27H23F3N2O5S

Molecular Weight:: 544.54

MDL Number:

MOL File:: 2108603-03-6.mol

Last updated:2023-05-21 10:59:17

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1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Properties

Boiling point	692.2±65.0 °C(Predicted)
Density	1.427±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.5 mg/ml; DMSO: 10 mg/ml; Ethanol: .05 mg/ml
form	A crystalline solid
pka	-6.05±0.20(Predicted)

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	72510	CAY10406	2108603-03-6	1mg	$29	2024-03-01	Buy
Cayman Chemical	72510	CAY10406	2108603-03-6	5mg	$121	2024-03-01	Buy
Cayman Chemical	72510	CAY10406	2108603-03-6	10mg	$216	2024-03-01	Buy
Cayman Chemical	72510	CAY10406	2108603-03-6	100mg	$1601	2024-03-01	Buy

Product number	Packaging	Price	Buy
72510	1mg	$29	Buy
72510	5mg	$121	Buy
72510	10mg	$216	Buy
72510	100mg	$1601	Buy

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Chemical Properties,Uses,Production

Description

CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits K_i values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are ''effector caspases'' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406.

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Preparation Products And Raw materials

Raw materials

Preparation Products

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Suppliers

Global( 5)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7980	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8739	58

Supplier	Advantage
Shanghai Hongye Biotechnology Co. Ltd	58
TargetMol Chemicals Inc.	58
Shanghai Yiyan Biotechnology Co. , Ltd.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione CAY10406,CAY-10406 1H-Indole-2,3-dione, 1-(phenylmethyl)-5-[[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]-1-pyrrolidinyl]sulfonyl]- (S)-1-benzyl-5-(1-[2-(phenoxy-p-trifluoromethyl)-pyrrolidynyl]-sulfonyl)-isatin 2108603-03-6