ChemicalBook >제품 카탈로그 >1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione 구조식 이미지

카스 번호:: 2108603-03-6

상품명:: 1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

동의어(영문):: CAY10406,CAY-10406;(S)-1-benzyl-5-(1-[2-(phenoxy-p-trifluoromethyl)-pyrrolidynyl]-sulfonyl)-isatin;1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione;1H-Indole-2,3-dione, 1-(phenylmethyl)-5-[[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]-1-pyrrolidinyl]sulfonyl]-

CBNumber:: CB83858099

분자식:: C27H23F3N2O5S

포뮬러 무게:: 544.54

MOL 파일:: 2108603-03-6.mol

속성

안전

용도

공급 업체 5

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione 속성

끓는 점: 692.2±65.0 °C(Predicted)

밀도: 1.427±0.06 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.5 mg/ml; DMSO: 10 mg/ml; Ethanol: .05 mg/ml

물리적 상태: 결정성 고체

산도 계수 (pKa): -6.05±0.20(Predicted)

안전

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione C화학적 특성, 용도, 생산

개요

CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits K_i values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are ''effector caspases'' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406.

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione 준비 용품 및 원자재

원자재

준비 용품

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione 공급 업체

글로벌( 5)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7980	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8739	58