1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

2108603-03-6

CAS-Nr.: 2108603-03-6

Englisch Name:: 1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione

Synonyma:: CAY10406,CAY-10406;(S)-1-benzyl-5-(1-[2-(phenoxy-p-trifluoromethyl)-pyrrolidynyl]-sulfonyl)-isatin;1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione;1H-Indole-2,3-dione, 1-(phenylmethyl)-5-[[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]-1-pyrrolidinyl]sulfonyl]-

CBNumber:: CB83858099

Summenformel:: C27H23F3N2O5S

Molgewicht:: 544.54

MOL-Datei:: 2108603-03-6.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 5

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Eigenschaften

Siedepunkt:: 692.2±65.0 °C(Predicted)

Dichte: 1.427±0.06 g/cm3(Predicted)

storage temp.: Store at -20°C

Löslichkeit: DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:2): 0.5 mg/ml; DMSO: 10 mg/ml; Ethanol: .05 mg/ml

Aggregatzustand: A crystalline solid

pka: -6.05±0.20(Predicted)

Sicherheit

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

CAY10406 is a trifluoromethyl analog of an isatin sulfonamide compound that selectively inhibits caspases 3 and 7. The non-trifluoromethyl compound exhibits K_i values of 1.2 nM and 6 nM for caspases 3 and 7, respectively. For all of the other caspases tested, it is 100 to 1,000 times less potent. Caspases 3 and 7 are ''effector caspases'' that are downstream from the initiating steps of apoptosis, and are implicated in the main proteolytic processing of the apoptotic signal. No data is currently available for caspase inhibition by CAY10406.

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 5)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	23963	58
Shanghai Yiyan Biotechnology Co. , Ltd.	021-69985186 13611928337	3427709316@qq.com	China	7980	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8739	58

1-benzyl-5-[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]pyrrolidin-1-yl]sulfonylindole-2,3-dione
CAY10406,CAY-10406
1H-Indole-2,3-dione, 1-(phenylmethyl)-5-[[(2S)-2-[[4-(trifluoromethyl)phenoxy]methyl]-1-pyrrolidinyl]sulfonyl]-
(S)-1-benzyl-5-(1-[2-(phenoxy-p-trifluoromethyl)-pyrrolidynyl]-sulfonyl)-isatin
2108603-03-6