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ChemicalBook >> CAS DataBase List >> 17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA

17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA price.
  • $62 - $477
  • Product name: 17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA
  • CAS: 221246-34-0
  • MF: C24H31F3O5
  • MW: 456.5
  • EINECS:
  • MDL Number:MFCD05863954
  • Synonyms:9ALPHA,11ALPHA,15S-TRIHYDROXY-17-TRIFLUOROMETHYLPHENYL-18,19,20-TRINOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;17-trifluoromethylphenyl trinor Prostaglandin F2α;17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA;CMLNDCUXASGBMQ-NQUQXYBYSA-N;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, (5Z)-;17-trifluoromethylphenyl trinor Prostaglandin F2α
3 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 1mg
  • 5mg
  • 10mg
  • ManufacturerCayman Chemical
  • Product number16890
  • Product description17-trifluoromethylphenyl trinor Prostaglandin F2α ≥98%
  • Packaging1mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16890
  • Product description17-trifluoromethylphenyl trinor Prostaglandin F2α ≥98%
  • Packaging5mg
  • Price$270
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16890
  • Product description17-trifluoromethylphenyl trinor Prostaglandin F2α ≥98%
  • Packaging10mg
  • Price$477
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 16890 17-trifluoromethylphenyl trinor Prostaglandin F2α ≥98% 1mg $62 2024-03-01 Buy
Cayman Chemical 16890 17-trifluoromethylphenyl trinor Prostaglandin F2α ≥98% 5mg $270 2024-03-01 Buy
Cayman Chemical 16890 17-trifluoromethylphenyl trinor Prostaglandin F2α ≥98% 10mg $477 2024-03-01 Buy

Properties

Boiling point :593.0±50.0 °C(Predicted)
Density :1.296±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
pka :4.76±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trinor PGF2α would act very much like the free acid of travoprost. 17-phenyl trinor PGF2α is a potent luteolytic and abortifacient, with a potency equal to or greater than fluprostenol and cloprostenol.

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