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ChemicalBook >> VEGFR2 Kinase Inhibitor II

VEGFR2 Kinase Inhibitor II

VEGFR2 Kinase Inhibitor II price.
  • $85 - $661
  • Product name: VEGFR2 Kinase Inhibitor II
  • CAS: 288144-20-7
  • MF: C17H15BrN2O
  • MW: 343.22
  • EINECS:-0
  • MDL Number:MFCD03453583
  • Synonyms:VEGFR2 Kinase Inhibitor II;(3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one;VEGFR2 Kinase Inhibitor II - CAS 288144-20-7 - Calbiochem;2H-Indol-2-one, 5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-, (3Z)-;VEGFR2 Kinase Inhibitor II,VEGFR-2 Kinase Inhibitor II
3 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerCayman Chemical
  • Product number17544
  • Product descriptionVEGFR2 Kinase Inhibitor II ≥95%
  • Packaging500μg
  • Price$85
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17544
  • Product descriptionVEGFR2 Kinase Inhibitor II ≥95%
  • Packaging1mg
  • Price$158
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17544
  • Product descriptionVEGFR2 Kinase Inhibitor II ≥95%
  • Packaging5mg
  • Price$661
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 17544 VEGFR2 Kinase Inhibitor II ≥95% 500μg $85 2024-03-01 Buy
Cayman Chemical 17544 VEGFR2 Kinase Inhibitor II ≥95% 1mg $158 2024-03-01 Buy
Cayman Chemical 17544 VEGFR2 Kinase Inhibitor II ≥95% 5mg $661 2024-03-01 Buy

Properties

storage temp. :-20C
solubility :DMF: 20 mg/ml; DMSO: 10 mg/ml
form :Brown solid

Safety Information

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Description

Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2’s kinase activity (IC50 = 70 nM). It less potently inhibits the platelet-derived growth factor receptor β (PDGFRβ; IC50 = 920 nM) and related receptor and non-receptor tyrosine kinases. VEGFR2 kinase inhibitor II blocks the growth of human umbilical vein endothelial cells stimulated with either VEGF or PDGF (IC50s = 110 nM and 2 μM, respectively).