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ChemicalBook >> CAS DataBase List >> 2,2-bis(4-fluorophenyl)-2-phenyl-acetamide

2,2-bis(4-fluorophenyl)-2-phenyl-acetamide

2,2-bis(4-fluorophenyl)-2-phenyl-acetamide price.
  • $12 - $2975
  • Product name: 2,2-bis(4-fluorophenyl)-2-phenyl-acetamide
  • CAS: 289656-45-7
  • MF: C20H15F2NO
  • MW: 323.34
  • EINECS:
  • MDL Number:MFCD09027349
  • Synonyms:2,2-bis(4-fluorophenyl)-2-phenyl-acetamide;Benzeneacetamide, 4-fluoro-a-(4-fluorophenyl)-a-phenyl-;4-Fluoro-alpha-(4-fluorophenyl)-alpha-phenylbenzeneacetamide;4-Fluoro-A-(4-Fluorophenyl)-A-Phenyl-BenzeneacetaMide;ICA 17043;Senicapoc;ICA-17043;ICA 17043;ICA17043;Benzeneacetamide, 4-fluoro-α-(4-fluorophenyl)-α-phenyl-
27 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • JR MediChem
  • Matrix Scientific
Package
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  • 50mg
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  • 250mg
  • 500mg
  • 0.5G
  • 1g
  • 5g
  • 10g
  • ManufacturerAK Scientific
  • Product numberY5374
  • Product description2,2-bis(4-Fluorophenyl)-2-phenylacetamide
  • Packaging10mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY5374
  • Product description2,2-bis(4-Fluorophenyl)-2-phenylacetamide
  • Packaging50mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY5374
  • Product description2,2-bis(4-Fluorophenyl)-2-phenylacetamide
  • Packaging250mg
  • Price$172
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging1mg
  • Price$12
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging5mg
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging10mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging50mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging100mg
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging250mg
  • Price$195
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging1g
  • Price$498
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA239412
  • Product descriptionSenicapoc 98+%
  • Packaging10g
  • Price$2975
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008101
  • Product descriptionICA-17043 95.00%
  • Packaging0.5G
  • Price$414
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS100781
  • Product descriptionSenicapoc
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS100781
  • Product descriptionSenicapoc
  • Packaging50mg
  • Price$262.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29679
  • Product descriptionSenicapoc
  • Packaging50mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29679
  • Product descriptionSenicapoc
  • Packaging100mg
  • Price$57
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y5374 2,2-bis(4-Fluorophenyl)-2-phenylacetamide 10mg $84 2021-12-16 Buy
AK Scientific Y5374 2,2-bis(4-Fluorophenyl)-2-phenylacetamide 50mg $112 2021-12-16 Buy
AK Scientific Y5374 2,2-bis(4-Fluorophenyl)-2-phenylacetamide 250mg $172 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 1mg $12 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 5mg $27 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 10mg $39 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 50mg $88 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 100mg $132 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 250mg $195 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 1g $498 2021-12-16 Buy
Ambeed A239412 Senicapoc 98+% 10g $2975 2021-12-16 Buy
American Custom Chemicals Corporation API0008101 ICA-17043 95.00% 0.5G $414 2021-12-16 Buy
Biosynth Carbosynth FS100781 Senicapoc 10mg $75 2021-12-16 Buy
Biosynth Carbosynth FS100781 Senicapoc 50mg $262.5 2021-12-16 Buy
Cayman Chemical 29679 Senicapoc 50mg $32 2024-03-01 Buy
Cayman Chemical 29679 Senicapoc 100mg $57 2024-03-01 Buy

Properties

Melting point :180-181 °C(Solv: hexane (110-54-3); dichloromethane (75-09-2))
Boiling point :460.7±45.0 °C(Predicted)
Density :1.250±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO : 50 mg/mL (154.64 mM; Need ultrasonic)
form :Powder
pka :15.41±0.50(Predicted)
color :White to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Senicapoc is an inhibitor of intermediate conductance calcium-activated potassium (IKCa1/KCa3.1) channels. It inhibits rubidium efflux from and dehydration of isolated human red blood cells (RBCs) induced by the calcium ionophore A23187 (; IC50s = 11 and 30 nM, respectively). Senicapoc (10 mg/kg twice per day) reduces IKCa1/KCa3.1 channel activity, increases potassium levels in RBCs, and decreases erythrocyte density in the SAD transgenic mouse model of sickle cell disease. It inhibits IL-2, IFN-γ, IL-12, and IL-17A production in CD3+ T cells stimulated with phorbol 12-myristate 13-acetate (PMA; ) and ionomycin (Item Nos. 10004974 | 11932) when used at a concentration of 1 μM. Senicapoc (100 mg/kg) increases the paw withdrawal threshold in a rat model of chronic constriction injury (CCI) of the sciatic nerve.