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ChemicalBook >> CAS DataBase List >> 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one

5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one

5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one price.
  • $40 - $1900
  • Product name: 5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one
  • CAS: 297180-15-5
  • MF: C15H10BrN3OS
  • MW: 360.23
  • EINECS:
  • MDL Number:
  • Synonyms:5-bromo-5'-phenyl-1,2',3,3'-tetrahydrospiro[2H-indole-3,2'-(1,3,4)-thiadiazole]-2-one;5-bromo-5'-phenyl-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-2(1H)-one;CB16.2 aka;Spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one, 5-bromo-5'-phenyl-;5-bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one;5-Bromo-5’phenylspiro[1H-indole-3,2’-3H-1,3,4-thiadiazole]-2-one;5-bromo-5'-phenyl-spiro[3H-indole-3,2'(3'H)-[1,3,4]thiadiazol]-2(1H)-one;Lipofermata,Inhibitor,Bacterial,inhibit
19 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number8804CJ
  • Product descriptionLipofermata
  • Packaging5mg
  • Price$191
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8804CJ
  • Product descriptionLipofermata
  • Packaging50mg
  • Price$604
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1145370
  • Product description5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+%
  • Packaging5mg
  • Price$169
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1145370
  • Product description5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+%
  • Packaging10mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1145370
  • Product description5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+%
  • Packaging25mg
  • Price$286
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1145370
  • Product description5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+%
  • Packaging50mg
  • Price$372
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009861
  • Product descriptionLIPOFERMATA 95.00%
  • Packaging5MG
  • Price$454.56
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0084
  • Product descriptionLipofermata 99%
  • Packaging1mg
  • Price$131
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0084
  • Product descriptionLipofermata 99%
  • Packaging5mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBISN0084
  • Product descriptionLipofermata 99%
  • Packaging10mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25869
  • Product descriptionLipofermata ≥98%
  • Packaging5mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25869
  • Product descriptionLipofermata ≥98%
  • Packaging10mg
  • Price$72
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25869
  • Product descriptionLipofermata ≥98%
  • Packaging25mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25869
  • Product descriptionLipofermata ≥98%
  • Packaging50mg
  • Price$236
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066519
  • Product descriptionLipofermata 99.84%
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066519
  • Product descriptionLipofermata 99.84%
  • Packaging10mg
  • Price$280
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8804CJ Lipofermata 5mg $191 2021-12-16 Buy
AK Scientific 8804CJ Lipofermata 50mg $604 2021-12-16 Buy
Ambeed A1145370 5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+% 5mg $169 2021-12-16 Buy
Ambeed A1145370 5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+% 10mg $220 2021-12-16 Buy
Ambeed A1145370 5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+% 25mg $286 2021-12-16 Buy
Ambeed A1145370 5-Bromo-5'-phenyl-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-2-one 98+% 50mg $372 2021-12-16 Buy
American Custom Chemicals Corporation INB0009861 LIPOFERMATA 95.00% 5MG $454.56 2021-12-16 Buy
Apolloscientific BISN0084 Lipofermata 99% 1mg $131 2021-12-16 Buy
Apolloscientific BISN0084 Lipofermata 99% 5mg $240 2021-12-16 Buy
Apolloscientific BISN0084 Lipofermata 99% 10mg $385 2021-12-16 Buy
Cayman Chemical 25869 Lipofermata ≥98% 5mg $40 2024-03-01 Buy
Cayman Chemical 25869 Lipofermata ≥98% 10mg $72 2024-03-01 Buy
Cayman Chemical 25869 Lipofermata ≥98% 25mg $139 2024-03-01 Buy
Cayman Chemical 25869 Lipofermata ≥98% 50mg $236 2024-03-01 Buy
ChemScene CS-0066519 Lipofermata 99.84% 5mg $160 2021-12-16 Buy
ChemScene CS-0066519 Lipofermata 99.84% 10mg $280 2021-12-16 Buy

Properties

Density :1.76±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :Soluble in DMSO (up to 20 mg/ml).
pka :0.44±0.20(Predicted)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase? as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Lipofermata (297180-15-5) is an inhibitor of fatty acid transport protein 2 (FATP2; IC50?= 4.84 μM).1?It does not inhibit glucose transport or the activity of long chain acyl-CoA synthetase. It prevented palmitate-mediated oxidative stress, induction of BiP and CHOP, and cell death in a dose-dependent manner in hsHepG2 and mINS-1E cells suggesting utility in preventing fatty acid-mediated cell death pathways and lipotoxic disease.2?Inhibition was specific for long and very long chain fatty acids but not medium (C6-C10) acids. Lipofermata abrogates lipid transport into melanoma cells and reduces melanoma growth and invasion.3

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