3-CARBETHOXYUMBELIFERONE
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- $32 - $925.6
- Product name: 3-CARBETHOXYUMBELIFERONE
- CAS: 6093-71-6
- MF: C12H10O5
- MW: 234.2
- EINECS:
- MDL Number:MFCD00017641
- Synonyms:AURORA 9226;ETHYL 3-UMBELLIFERYLCARBOXYLATE;7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID ETHYL ESTER;AKOS BBS-00008132;3-CARBETHOXYUMBELIFERONE;UMBELLIFERONE 3-CARBOXYLIC ACID ETHYL ESTER;Ethyl 7-hydroxy-2-oxo-2H-chroMene-3-carboxylate;Ethyl 7-Hydroxycoumarin-3-carboxylate
29 prices
Selected condition：
Brand
- AHH
- AK Scientific
- Alichem
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- Chem-Impex
- Crysdot
- CSNpharm
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 100MG
- 250mg
- 50mg
- 200mg
- 10
- 50
- 1g
- 5g
- 10g
- ManufacturerAHH
- Product numberMT-12836
- Product descriptionEthyl3-umbelliferylcarboxylate 98%
- Packaging1g
- Price$678
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8298AJ
- Product description7-Hydroxycoumarin-3-carboxylic acid ethyl ester
- Packaging200mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number6093716
- Product descriptionEthyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate
- Packaging1g
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number6093716
- Product descriptionEthyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate
- Packaging5g
- Price$566.5
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number6093716
- Product descriptionEthyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate
- Packaging10g
- Price$925.6
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA291718
- Product descriptionEthyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97%
- Packaging250mg
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA291718
- Product descriptionEthyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97%
- Packaging1g
- Price$266
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA291718
- Product descriptionEthyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97%
- Packaging5g
- Price$617
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0069843
- Product description7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID ETHYL ESTER 95.00%
- Packaging100MG
- Price$774.95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7740
- Product descriptionYZ9
- Packaging10mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7740
- Product descriptionYZ9
- Packaging50mg
- Price$597
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15352
- Product descriptionYZ9 ≥98%
- Packaging5mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15352
- Product descriptionYZ9 ≥98%
- Packaging10mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15352
- Product descriptionYZ9 ≥98%
- Packaging50mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15352
- Product descriptionYZ9 ≥98%
- Packaging100mg
- Price$214
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM162229
- Product descriptionethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97%
- Packaging1g
- Price$163
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AHH | MT-12836 | Ethyl3-umbelliferylcarboxylate 98% | 1g | $678 | 2021-12-16 | Buy |
| AK Scientific | 8298AJ | 7-Hydroxycoumarin-3-carboxylic acid ethyl ester | 200mg | $340 | 2021-12-16 | Buy |
| Alichem | 6093716 | Ethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate | 1g | $168 | 2021-12-16 | Buy |
| Alichem | 6093716 | Ethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate | 5g | $566.5 | 2021-12-16 | Buy |
| Alichem | 6093716 | Ethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate | 10g | $925.6 | 2021-12-16 | Buy |
| Ambeed | A291718 | Ethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97% | 250mg | $97 | 2021-12-16 | Buy |
| Ambeed | A291718 | Ethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97% | 1g | $266 | 2021-12-16 | Buy |
| Ambeed | A291718 | Ethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97% | 5g | $617 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0069843 | 7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID ETHYL ESTER 95.00% | 100MG | $774.95 | 2021-12-16 | Buy |
| ApexBio Technology | B7740 | YZ9 | 10mg | $140 | 2021-12-16 | Buy |
| ApexBio Technology | B7740 | YZ9 | 50mg | $597 | 2021-12-16 | Buy |
| Cayman Chemical | 15352 | YZ9 ≥98% | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15352 | YZ9 ≥98% | 10mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 15352 | YZ9 ≥98% | 50mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 15352 | YZ9 ≥98% | 100mg | $214 | 2024-03-01 | Buy |
| Chemenu | CM162229 | ethyl7-hydroxy-2-oxo-2H-chromene-3-carboxylate 97% | 1g | $163 | 2021-12-16 | Buy |
Properties
Melting point :170.0 to 174.0 °C
Boiling point :448.3±45.0 °C(Predicted)
Density :1.397±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :7.32±0.20(Predicted)
form :powder
color :white to beige
λmax :398nm(EtOH)(lit.)
CAS DataBase Reference :6093-71-6
Boiling point :448.3±45.0 °C(Predicted)
Density :1.397±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :7.32±0.20(Predicted)
form :powder
color :white to beige
λmax :398nm(EtOH)(lit.)
CAS DataBase Reference :6093-71-6
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Cells that are rapidly proliferating or hypoxic emphasize glycolysis over oxidative phosphorylation to meet energy needs. During glycolysis, fructose 6-phosphate (F6P) is phosphorylated by 6-phosphofructo-2-kinases (PFKs) to generate fructose 2,6-bisphosphate. As PFK family members also mediate the reverse reaction as fructose 2,6-bisphosphatases, these enzymes are known as PFKFB family members. Notably, PFKFB3 is overexpressed in a wide variety of cancer cell lines. YZ9 is a potent inhibitor of PFKFB3, with an IC50 value of 183 nM in vitro. It avidly competes with F6P at PFKFB3 (Ki = 94 nM). YZ9 is also cell permeable, inhibiting the growth of HeLa cells with a GI50 value of 2.7 μM.Related product price
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