ChemicalBook >> CAS DataBase List >>3-CARBETHOXYUMBELIFERONE
3-CARBETHOXYUMBELIFERONE
- CAS No.
- 6093-71-6
- Chemical Name:
- 3-CARBETHOXYUMBELIFERONE
- Synonyms
- YZ9;AURORA 9226;AKOS BBS-00008132;YZ9, 10 mM in DMSO;YZ9, PFKFB3 inhibitor;3-CARBETHOXYUMBELIFERONE;ETHYL 3-UMBELLIFERYLCARBOXYLATE;ethyl umbelliferone-3-carboxylate;Ethyl 7-Hydroxycoumarin-3-carboxylate;Ethyl7-Hydroxycoumarin-3-carboxylate>
- CBNumber:
- CB1302710
- Molecular Formula:
- C12H10O5
- Molecular Weight:
- 234.2
- MDL Number:
- MFCD00017641
- MOL File:
- 6093-71-6.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 170.0 to 174.0 °C |
|---|---|
| Boiling point | 448.3±45.0 °C(Predicted) |
| Density | 1.397±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | DMSO: soluble5mg/mL, clear (warmed) |
| pka | 7.32±0.20(Predicted) |
| form | powder |
| color | white to beige |
| λmax | 398nm(EtOH)(lit.) |
| CAS DataBase Reference | 6093-71-6 |
| FDA UNII | X538NC636R |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H227 |
| Precautionary statements | P501-P210-P280-P370+P378-P403+P235 |
| WGK Germany | 3 |
| HS Code | 29339900 |
3-CARBETHOXYUMBELIFERONE price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1270 | 7-Hydroxycoumarin-3-carboxylic acid ethyl ester ≥98% (HPLC) | 6093-71-6 | 10mg | $94.3 | 2024-03-01 | Buy |
| TCI Chemical | E1017 | Ethyl 7-Hydroxycoumarin-3-carboxylate >98.0%(GC) | 6093-71-6 | 200mg | $174 | 2024-03-01 | Buy |
| Cayman Chemical | 15352 | YZ9 ≥98% | 6093-71-6 | 5mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 15352 | YZ9 ≥98% | 6093-71-6 | 10mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 15352 | YZ9 ≥98% | 6093-71-6 | 50mg | $139 | 2024-03-01 | Buy |
3-CARBETHOXYUMBELIFERONE Chemical Properties,Uses,Production
Chemical Properties
Brown solid
Uses
Z9 is a potent inhibitor of PFKFB3, a member of 6-phosphofructo-2-kinases family. It avidly competes with fructose 6-phosphate (F6P) at PFKFB3. YZ9 is also cell permeable, inhibiting the growth of HeLa cells.
Biological Activity
YZ9 is a 5, 6, 7, 8-tetrahydroxy-2-(4-hydroxyphenyl) chromen-4-one (N4A) inhibitor.', 'YZ9 is a potent inhibitor of PFKFB3 (6-phosphfructo-2-kinase/fructose-2,6-bisphosphatase) with an IC50 = 183 nM. PFKFB3 is over expressed in many cancers and catalyzes the production of fructose-2,6-bisphosphate, which can potentiate PFK1 activity, enhancing glycolysis in tumor cells. YZ9 dose dependently inhibits proliferation of HeLa cells.
3-CARBETHOXYUMBELIFERONE Preparation Products And Raw materials
Raw materials
2,4-Dihydroxybenzaldehyde
Ethyl acetate
Diethyl malonate
PETROLEUM ETHER
4,4,4-TRICHLOROACETOACETIC ACID ETHYL ESTER
1of3
Preparation Products
Global( 102)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29809 | 58 |
| Jiangxi Lotchem Co.,Ltd. | +8615270827708 | lancetu@jxlotchem.com | CHINA | 338 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22787 | 58 |
| Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| Hebei Weibang Biotechnology Co., Ltd | +8617732866630 | bess@weibangbio.com | China | 18147 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from 3-CARBETHOXYUMBELIFERONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-19 | YZ9
6093-71-6
|
US $50.00 / mg | 99.13% | 10g | TargetMol Chemicals Inc. | ||
 |
2021-11-02 | 3-CARBETHOXYUMBELIFERONE
6093-71-6
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-12-20 | 3-CARBETHOXYUMBELIFERONE
6093-71-6
|
US $1.00 / KG | 1KG | 99% | KG/T | Career Henan Chemical Co |
-
- YZ9
6093-71-6
- US $50.00 / mg
- 99.13%
- TargetMol Chemicals Inc.
-
- 3-CARBETHOXYUMBELIFERONE
6093-71-6
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 3-CARBETHOXYUMBELIFERONE
6093-71-6
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
6093-71-6(3-CARBETHOXYUMBELIFERONE)Related Search:
AURORA 9226
ETHYL 3-UMBELLIFERYLCARBOXYLATE
7-HYDROXYCOUMARIN-3-CARBOXYLIC ACID ETHYL ESTER
AKOS BBS-00008132
3-CARBETHOXYUMBELIFERONE
UMBELLIFERONE 3-CARBOXYLIC ACID ETHYL ESTER
Ethyl 7-hydroxy-2-oxo-2H-chroMene-3-carboxylate
Ethyl 7-Hydroxycoumarin-3-carboxylate
3-CARBETHOXYUMBELIFERONE7-Hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethyl ester
YZ9
ethyl 7-hydroxy-2-oxochromene-3-carboxylate
ethyl umbelliferone-3-carboxylate
7-Hydroxycoumarin-3-carboxylic acid ethyl ester ,98%
Ethyl 7-hydroxy-2-oxo-2H-1-benzopyran-3-carboxylate
Ethyl7-Hydroxycoumarin-3-carboxylate>
2H-1-Benzopyran-3-carboxylic acid, 7-hydroxy-2-oxo-, ethyl ester
3-CARBETHOXYUMBELIFERONE ISO 9001：2015 REACH
YZ9, PFKFB3 inhibitor
YZ9, 10 mM in DMSO
6093-71-6
Fluorogenic
Activity
Aromatic Esters