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ChemicalBook >> CAS DataBase List >> 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID

2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID

2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID price.
  • $32 - $1802
  • Product name: 2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID
  • CAS: 321674-73-1
  • MF: C21H17NO3
  • MW: 331.36
  • EINECS:
  • MDL Number:MFCD11112195
  • Synonyms:2-[[(2E)-3-(2-NAPHTHALENYL)-1-OXO-2-BUTEN-1-YL]AMINO]BENZOIC ACID;BIBR 1532;2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl1-yl]amino]benzoicacid;2-[[(2E)-3-(2-Naphthalenyl)-1-oxo-2-butenyl]amino]benzoic acid;(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoic acid;BIBR 1532, >=98%;BIBR 1532;BIBR-1532;CS-1061
29 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10
  • 50
  • 1MG
  • 10mg
  • 25mg
  • 10mM(in 1mL DMSO)
  • 50MG
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX7524
  • Product description(E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoicacid
  • Packaging10mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000875
  • Product descriptionBIBR-1532 95.00%
  • Packaging1MG
  • Price$135.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000875
  • Product descriptionBIBR-1532 95.00%
  • Packaging10MG
  • Price$709.46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000875
  • Product descriptionBIBR-1532 95.00%
  • Packaging50MG
  • Price$1267.33
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1945
  • Product descriptionBIBR1532
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1945
  • Product descriptionBIBR1532
  • Packaging10mM(in 1mL DMSO)
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1945
  • Product descriptionBIBR1532
  • Packaging25mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1945
  • Product descriptionBIBR1532
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2301
  • Product descriptionBIBR1532 99%
  • Packaging5mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180843
  • Product descriptionBIBR-1532 >98%
  • Packaging100mg
  • Price$606.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180843
  • Product descriptionBIBR-1532 >98%
  • Packaging250mg
  • Price$912.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180843
  • Product descriptionBIBR-1532 >98%
  • Packaging1000mg
  • Price$1802
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16608
  • Product descriptionBIBR 1532 ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16608
  • Product descriptionBIBR 1532 ≥95%
  • Packaging5mg
  • Price$78
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16608
  • Product descriptionBIBR 1532 ≥95%
  • Packaging10mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16608
  • Product descriptionBIBR 1532 ≥95%
  • Packaging50mg
  • Price$517
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7524 (E)-2-(3-(naphthalen-2-yl)but-2-enamido)benzoicacid 10mg $170 2021-12-16 Buy
American Custom Chemicals Corporation INB0000875 BIBR-1532 95.00% 1MG $135.45 2021-12-16 Buy
American Custom Chemicals Corporation INB0000875 BIBR-1532 95.00% 10MG $709.46 2021-12-16 Buy
American Custom Chemicals Corporation INB0000875 BIBR-1532 95.00% 50MG $1267.33 2021-12-16 Buy
ApexBio Technology A1945 BIBR1532 5mg $50 2021-12-16 Buy
ApexBio Technology A1945 BIBR1532 10mM(in 1mL DMSO) $99 2021-12-16 Buy
ApexBio Technology A1945 BIBR1532 25mg $150 2021-12-16 Buy
ApexBio Technology A1945 BIBR1532 100mg $400 2021-12-16 Buy
Axon Medchem Axon2301 BIBR1532 99% 5mg $77 2021-12-16 Buy
Biorbyt Ltd orb180843 BIBR-1532 >98% 100mg $606.9 2021-12-16 Buy
Biorbyt Ltd orb180843 BIBR-1532 >98% 250mg $912.9 2021-12-16 Buy
Biorbyt Ltd orb180843 BIBR-1532 >98% 1000mg $1802 2021-12-16 Buy
Cayman Chemical 16608 BIBR 1532 ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 16608 BIBR 1532 ≥95% 5mg $78 2024-03-01 Buy
Cayman Chemical 16608 BIBR 1532 ≥95% 10mg $120 2024-03-01 Buy
Cayman Chemical 16608 BIBR 1532 ≥95% 50mg $517 2024-03-01 Buy

Properties

Melting point :>173oC (dec.)
Boiling point :600.6±48.0 °C(Predicted)
Density :1.284
storage temp. :Store at RT
solubility :DMSO (Slightly), Methanol (Slightly, Sonicated)
form :Solid
pka :3.46±0.36(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

BIBR 1532 is a mixed-type non-competitive inhibitor of telomerase (IC50 = 93 nM) that has little effect on several mammalian DNA and RNA polymerases, bacterial DNA helicase, or HIV-1 reverse transcriptase. It specifically targets the telomerase reverse transcriptase catalytic subunit, TERT. Through its effects on telomerase, BIBR 1532 induces senescence or apoptosis in cancer cells. Apoptosis in triple negative breast cancer cells induced by BIBR 1532 is potentiated by glucose restriction.

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