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ChemicalBook >> [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester

[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester

[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester price.
  • $44 - $1385
  • Product name: [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester
  • CAS: 353280-43-0
  • MF: C28H25NO7S
  • MW: 519.57
  • EINECS:
  • MDL Number:MFCD18086885
  • Synonyms:[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester;2-[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-propanedioic acid 1,3-dimethyl ester;S26948;S 26948 >=98% (HPLC);S26948,S-26948;Propanedioic acid, 2-[[4-[2-(6-benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-, 1,3-dimethyl ester
10 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number4509CR
  • Product descriptionDimethyl2-[[4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3-yl)ethoxy]phenyl]methyl]propanedioate
  • Packaging5mg
  • Price$253
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBRS0000846
  • Product descriptionS 26948 95.00%
  • Packaging5MG
  • Price$502.72
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7471
  • Product descriptionS 26948
  • Packaging10mg
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7471
  • Product descriptionS 26948
  • Packaging50mg
  • Price$1385
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29722
  • Product descriptionS 26948
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29722
  • Product descriptionS 26948
  • Packaging5mg
  • Price$140
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0510
  • Product descriptionS 26948 ≥98% (HPLC)
  • Packaging5mg
  • Price$144
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0510
  • Product descriptionS 26948 ≥98% (HPLC)
  • Packaging25mg
  • Price$568
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberS960015
  • Product descriptionS 26948
  • Packaging50mg
  • Price$875
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256585
  • Product descriptionS 26948
  • Packaging10mg
  • Price$480
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 4509CR Dimethyl2-[[4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3-yl)ethoxy]phenyl]methyl]propanedioate 5mg $253 2021-12-16 Buy
American Custom Chemicals Corporation BRS0000846 S 26948 95.00% 5MG $502.72 2021-12-16 Buy
ApexBio Technology B7471 S 26948 10mg $339 2021-12-16 Buy
ApexBio Technology B7471 S 26948 50mg $1385 2021-12-16 Buy
Cayman Chemical 29722 S 26948 1mg $44 2024-03-01 Buy
Cayman Chemical 29722 S 26948 5mg $140 2024-03-01 Buy
Sigma-Aldrich SML0510 S 26948 ≥98% (HPLC) 5mg $144 2024-03-01 Buy
Sigma-Aldrich SML0510 S 26948 ≥98% (HPLC) 25mg $568 2024-03-01 Buy
TRC S960015 S 26948 50mg $875 2021-12-16 Buy
Usbiological 256585 S 26948 10mg $480 2021-12-16 Buy

Properties

Melting point :65-67 °C(Solv: methanol (67-56-1))
Boiling point :687.3±65.0 °C(Predicted)
Density :1.312±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :DMSO: soluble10mg/mL (clear solution)
form :powder
pka :12.48±0.59(Predicted)
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

S26948 is a peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 8.83 nM in a transactivation assay). It is selective for PPARγ over PPARα, PPARβ/δ, and retinoid X receptor α (RXRα) at 10 μM. S26948 (30 mg/kg per day) decreases serum levels of glucose, triglycerides, non-esterified fatty acids, and insulin and increases hepatic palmitate oxidation in an ob/ob mouse model of type 2 diabetes. It decreases plasma levels of triglycerides and total and non-HDL cholesterol and the surface area of atherosclerotic lesions in the aortic sinus in an E2-KI transgenic mouse model of dyslipidemia and atherosclerosis fed a Western diet when administered at a dose of 30 mg/kg.