4-AMINO-1,8-NAPHTHALIMIDE
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- $44 - $1022.42
- Product name: 4-AMINO-1,8-NAPHTHALIMIDE
- CAS: 1742-95-6
- MF: C12H8N2O2
- MW: 212.2
- EINECS:217-110-1
- MDL Number:MFCD00006921
- Synonyms:4-Amino-1,8-naphthalenedicarbimide;4-Amino-1,8-naphthalenedicarboximide;4-Aminonaphthalene-1,8-dicarbimide;6-Amino-2,3-dihydro-1H-benzo[de]isoquinoline-1,3-dione;6-Amino-2H-benzo[de]isoquinoline-1,3-dione;4-Amino-1,8-naphthalimide,98%;6-amino-1h-benz(de)isoquinoline-3(2h)-dione ;6-amino-1h-benz[de]isoquinoline-3(2h)-dione
19 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- Alichem
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 20MG
- 50mg
- 100mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- ManufacturerAK Scientific
- Product number2616AL
- Product description4-Amino-1,8-naphthalimide
- Packaging250mg
- Price$127
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64358
- Product description4-Amino-1,8-naphthalimide, 95%
- Packaging100mg
- Price$48.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64358
- Product description4-Amino-1,8-naphthalimide, 95%
- Packaging1g
- Price$201.65
- Updated2024-03-01
- Buy
- ManufacturerAlichem
- Product number1742956
- Product description6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione
- Packaging5g
- Price$925.41
- Updated2021-12-16
- Buy
- ManufacturerAlichem
- Product number1742956
- Product description6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione
- Packaging10g
- Price$1022.42
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0011463
- Product description4-AMINO-1,8-NAPHTHALIMIDE 95.00%
- Packaging20MG
- Price$618.73
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA67151
- Product description4-Amino-1,8-naphthalimide
- Packaging250mg
- Price$57.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA67151
- Product description4-Amino-1,8-naphthalimide
- Packaging500mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA67151
- Product description4-Amino-1,8-naphthalimide
- Packaging1g
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA67151
- Product description4-Amino-1,8-naphthalimide
- Packaging2g
- Price$254
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA67151
- Product description4-Amino-1,8-naphthalimide
- Packaging5G
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18509
- Product description4-amino-1,8-Naphthalimide ≥95%
- Packaging10mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18509
- Product description4-amino-1,8-Naphthalimide ≥95%
- Packaging50mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18509
- Product description4-amino-1,8-Naphthalimide ≥95%
- Packaging100mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18509
- Product description4-amino-1,8-Naphthalimide ≥95%
- Packaging250mg
- Price$745
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD11232739
- Product description4-AMINO-1,8-NAPHTHALIMIDE 97%
- Packaging5g
- Price$466
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2616AL | 4-Amino-1,8-naphthalimide | 250mg | $127 | 2021-12-16 | Buy |
Alfa Aesar | J64358 | 4-Amino-1,8-naphthalimide, 95% | 100mg | $48.65 | 2024-03-01 | Buy |
Alfa Aesar | J64358 | 4-Amino-1,8-naphthalimide, 95% | 1g | $201.65 | 2024-03-01 | Buy |
Alichem | 1742956 | 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione | 5g | $925.41 | 2021-12-16 | Buy |
Alichem | 1742956 | 6-Amino-1H-benzo[de]isoquinoline-1,3(2H)-dione | 10g | $1022.42 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0011463 | 4-AMINO-1,8-NAPHTHALIMIDE 95.00% | 20MG | $618.73 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA67151 | 4-Amino-1,8-naphthalimide | 250mg | $57.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA67151 | 4-Amino-1,8-naphthalimide | 500mg | $90 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA67151 | 4-Amino-1,8-naphthalimide | 1g | $140 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA67151 | 4-Amino-1,8-naphthalimide | 2g | $254 | 2021-12-16 | Buy |
Biosynth Carbosynth | FA67151 | 4-Amino-1,8-naphthalimide | 5G | $550 | 2021-12-16 | Buy |
Cayman Chemical | 18509 | 4-amino-1,8-Naphthalimide ≥95% | 10mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 18509 | 4-amino-1,8-Naphthalimide ≥95% | 50mg | $193 | 2024-03-01 | Buy |
Cayman Chemical | 18509 | 4-amino-1,8-Naphthalimide ≥95% | 100mg | $341 | 2024-03-01 | Buy |
Cayman Chemical | 18509 | 4-amino-1,8-Naphthalimide ≥95% | 250mg | $745 | 2024-03-01 | Buy |
Crysdot | CD11232739 | 4-AMINO-1,8-NAPHTHALIMIDE 97% | 5g | $466 | 2021-12-16 | Buy |
Properties
Melting point :360 °C
Boiling point :352.04°C (rough estimate)
Density :1.105 g/mL at 25 °C(lit.)
vapor pressure :0Pa at 25℃
refractive index :1.6000 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO
form :Orange solid.
pka :9.53±0.20(Predicted)
color :Yellow to brown
Water Solubility :354mg/L at 25℃
LogP :1.08
CAS DataBase Reference :1742-95-6
EPA Substance Registry System :1H-Benz[de]isoquinoline-1,3(2H)-dione, 6-amino- (1742-95-6)
Boiling point :352.04°C (rough estimate)
Density :1.105 g/mL at 25 °C(lit.)
vapor pressure :0Pa at 25℃
refractive index :1.6000 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO
form :Orange solid.
pka :9.53±0.20(Predicted)
color :Yellow to brown
Water Solubility :354mg/L at 25℃
LogP :1.08
CAS DataBase Reference :1742-95-6
EPA Substance Registry System :1H-Benz[de]isoquinoline-1,3(2H)-dione, 6-amino- (1742-95-6)
Safety Information
Symbol(GHS): |
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Description
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis, particularly in response to reactive oxygen and nitrogen species. 4-amino-1,8-Naphthalimide (4-ANI) is an inhibitor of PARP (IC50 = 180 nM). It blocks radiation-induced PARP in cancer cells, potentiating the cytotoxicity of γ-radiation, although it is not cytotoxic in the absence of radiation. 4-ANI is used to study the role of PARP activity in various cell systems.Related product price
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